Niharika Malviya, Tracy Cheung, Joseph Kim, Kelli Aibel, Chihiro Okada, Nitya Abraham
{"title":"尿失禁、死亡率和虚弱之间的关系：来自大型队列研究的见解。","authors":"Niharika Malviya, Tracy Cheung, Joseph Kim, Kelli Aibel, Chihiro Okada, Nitya Abraham","doi":"10.1002/nau.70064","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study aims to explore the relationship between urinary incontinence (UI) and mortality in women, with a focus on the potential role of frailty and variations across UI subtypes.</p><p><strong>Methods: </strong>We analyzed 8967 women aged 40 and above who were part of the National Health and Nutrition Examination Survey (NHANES). Kaplan-Meier survival curves and Cox regression analyses were performed to assess the relationship between urge UI (UUI), stress UI (SUI), other UI (OUI) and all-cause mortality. These models were adjusted for demographic variables and frailty scores.</p><p><strong>Results: </strong>Approximately 45.8% of participants reported UI in the past year. Initial analysis showed a significant association between UI and increased mortality risk (hazard ratio [HR] = 1.478, 95% confidence interval [CI] 1.317-1.657, p < 0.001), persisting after controlling for frailty (HR = 1.151, 95% CI 1.022-1.297, p = 0.021). However, after adjusting for frailty and demographic factors, this association became non-significant.</p><p><strong>Conclusion: </strong>Women with UI exhibited a significantly increased risk of all-cause mortality, but this association did not hold after accounting for both key demographics and frailty.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Relationship Between Urinary Incontinence, Mortality, and Frailty: Insights From a Large Cohort Study.\",\"authors\":\"Niharika Malviya, Tracy Cheung, Joseph Kim, Kelli Aibel, Chihiro Okada, Nitya Abraham\",\"doi\":\"10.1002/nau.70064\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>This study aims to explore the relationship between urinary incontinence (UI) and mortality in women, with a focus on the potential role of frailty and variations across UI subtypes.</p><p><strong>Methods: </strong>We analyzed 8967 women aged 40 and above who were part of the National Health and Nutrition Examination Survey (NHANES). Kaplan-Meier survival curves and Cox regression analyses were performed to assess the relationship between urge UI (UUI), stress UI (SUI), other UI (OUI) and all-cause mortality. These models were adjusted for demographic variables and frailty scores.</p><p><strong>Results: </strong>Approximately 45.8% of participants reported UI in the past year. Initial analysis showed a significant association between UI and increased mortality risk (hazard ratio [HR] = 1.478, 95% confidence interval [CI] 1.317-1.657, p < 0.001), persisting after controlling for frailty (HR = 1.151, 95% CI 1.022-1.297, p = 0.021). However, after adjusting for frailty and demographic factors, this association became non-significant.</p><p><strong>Conclusion: </strong>Women with UI exhibited a significantly increased risk of all-cause mortality, but this association did not hold after accounting for both key demographics and frailty.</p>\",\"PeriodicalId\":19200,\"journal\":{\"name\":\"Neurourology and Urodynamics\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-05-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neurourology and Urodynamics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/nau.70064\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurourology and Urodynamics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/nau.70064","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
The Relationship Between Urinary Incontinence, Mortality, and Frailty: Insights From a Large Cohort Study.
Objective: This study aims to explore the relationship between urinary incontinence (UI) and mortality in women, with a focus on the potential role of frailty and variations across UI subtypes.
Methods: We analyzed 8967 women aged 40 and above who were part of the National Health and Nutrition Examination Survey (NHANES). Kaplan-Meier survival curves and Cox regression analyses were performed to assess the relationship between urge UI (UUI), stress UI (SUI), other UI (OUI) and all-cause mortality. These models were adjusted for demographic variables and frailty scores.
Results: Approximately 45.8% of participants reported UI in the past year. Initial analysis showed a significant association between UI and increased mortality risk (hazard ratio [HR] = 1.478, 95% confidence interval [CI] 1.317-1.657, p < 0.001), persisting after controlling for frailty (HR = 1.151, 95% CI 1.022-1.297, p = 0.021). However, after adjusting for frailty and demographic factors, this association became non-significant.
Conclusion: Women with UI exhibited a significantly increased risk of all-cause mortality, but this association did not hold after accounting for both key demographics and frailty.
期刊介绍：
Neurourology and Urodynamics welcomes original scientific contributions from all parts of the world on topics related to urinary tract function, urinary and fecal continence and pelvic floor function.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
