过期正畸结合材料对人原代牙龈成纤维细胞影响的体外研究。

Q2 Dentistry
Journal of Orthodontic Science Pub Date : 2025-03-25 eCollection Date: 2025-01-01 DOI:10.4103/jos.jos_67_24
Maysaa Z Khojah, Abdel-Rahman Youssef, Elham N Alsahafi
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引用次数: 0

摘要

目的:复合树脂和粘结剂在正畸治疗中是不可缺少的,需要对它们的细胞毒性作用进行彻底的了解,特别是当它们过期时。本研究旨在评价过期复合材料和粘结材料对人牙龈成纤维细胞(hGFs)的影响。材料和方法:采用直接暴露法对过期和未过期的复合树脂和粘结剂在hGFs上进行测试。在暴露后24和72小时进行活力测定、形态学评估和伤口愈合测定。结果:暴露于过期和未过期的材料会导致hGF活力显著降低和形态学改变。伤口愈合试验表明,暴露于这些材料后,hgf的迁移能力受损。结论:本研究强调了在正畸实践中谨慎选择材料、处理和监测的重要性,以减轻对牙龈组织的不良影响。妥善管理过期材料对于成本效益、减少浪费和患者安全至关重要。为了保证临床治疗的安全性和有效性,进一步研究过期材料对牙龈和牙周健康的长期影响是必要的。本研究为正畸粘接材料的生物相容性提供了有价值的见解,并强调了在使用正畸粘接材料时保持警惕以维护患者福利和治疗质量的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The effect of expired orthodontic bonding material on primary human gingival fibroblasts: In vitro study.

Aim: Composite resins and bonding agents are indispensable in orthodontic practice, necessitating a thorough understanding of their cytotoxic effects, particularly when expired. This study aimed to evaluate the influence of expired composite and bonding materials on human gingival fibroblasts (hGFs).

Materials and methods: Both expired and nonexpired composite resins and bonding agents were tested on hGFs using direct exposure methods. Viability assays, morphological evaluations, and wound healing assays were conducted at 24 and 72 hours post exposure.

Results: Exposure to both expired and nonexpired materials led to significant reductions in hGF viability and alterations in morphology. Wound healing assays demonstrated impaired migratory abilities of hGFs following exposure to these materials.

Conclusion: The study highlights the importance of prudent material selection, handling, and monitoring in orthodontic practice to mitigate adverse effects on gingival tissues. Proper management of expired materials is crucial for cost-effectiveness, waste reduction, and patient safety. Further research into the long-term impacts of expired materials on gingival and periodontal health is imperative to ensure clinical treatment safety and efficacy. This investigation provides valuable insights into the biocompatibility of orthodontic bonding materials and emphasizes the necessity for continued vigilance in their usage to uphold patient welfare and treatment quality.

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来源期刊
Journal of Orthodontic Science
Journal of Orthodontic Science Dentistry-Orthodontics
CiteScore
0.90
自引率
0.00%
发文量
46
审稿时长
19 weeks
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