阴茎假体的最新进展。

Mykoniatis Ioannis, Langas Georgios, Tsiakaras Stavros, Anastasiadis Anastasios, Van Renterghem Koenraad
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引用次数: 0

摘要

摘要:本文旨在对阴茎假体治疗勃起功能障碍(ED)的历史演变、类型、主要进展、临床结果和未来发展方向进行综述。对2000年1月至2024年4月期间发表的英文研究进行了全面的文献检索,使用的数据库包括PubMed、MEDLINE、Embase和Cochrane图书馆。搜索词包括“阴茎假体”、“阴茎植入物”、“可塑阴茎植入物”、“可充气阴茎假体”、“两件式IPP”、“三件式IPP”和“阴茎植入物进展”。纳入的研究集中在阴茎假体的发展,有效性和并发症。这些研究包括临床试验、随机对照试验、观察性研究、系统评价和荟萃分析。对数据进行定性和定量综合。阴茎假体自发明以来已经有了显著的发展,在延展性和充气式模型方面都有了显著的进步。可塑假体以其简单和可靠而闻名,它提供了一种半刚性的状态,对手部灵活性有限或正在进行抢救手术的患者有益。充气阴茎假体(ipp),特别是三件套模型,已经看到了实质性的技术进步,包括提高机械可靠性,减少抗生素涂层引起的感染率,以及更好的患者满意度。关键的创新包括亲水性涂层、聚对二甲苯微涂层和抗生素浸渍植入物的开发,这些都减少了并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Update on penile prosthesis.

Abstract: The aim of this narrative review is to provide a comprehensive overview of penile prostheses (PPs) for the treatment of erectile dysfunction (ED), exploring their historical evolution, types, key advancements, clinical outcomes, and future directions. A comprehensive literature search of studies published in English was conducted between January 2000 and April 2024, using databases including PubMed, MEDLINE, Embase, and the Cochrane Library. Search terms included "penile prosthesis", "penile implants", "malleable penile implant", "inflatable penile prosthesis", "two-piece IPP", "three-piece IPP", and "penile implant advancements". The included studies focused on the development, effectiveness, and complications of penile prostheses. These studies are clinical trials, randomized controlled trials, observational studies, systematic reviews, and meta-analyses. Data were synthesized qualitatively and quantitatively. Penile prostheses have significantly evolved since their invention, with notable advancements in both malleable and inflatable models. Malleable prostheses, known for their simplicity and reliability, offer a semirigid state that is beneficial for patients with limited hand dexterity or those undergoing salvage procedures. Inflatable penile prostheses (IPPs), particularly the three-piece models, have seen substantial technological improvements, including enhanced mechanical reliability, reduced infection rates due to antibiotic coatings, and better patient satisfaction. Key innovations include the development of hydrophilic coatings, parylene microcoatings, and antibiotic-impregnated implants, which have collectively reduced complications.

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