输血依赖性地中海贫血患者输血频率、铁蛋白和颈动脉内膜中膜厚度的关系。

Q4 Dentistry

Folia medica Pub Date : 2025-04-04 DOI:10.3897/folmed.67.e143457

Rahmat Cahyanur, Muhammad Ikhsan, Shabrina Tadjoedin, Devi Nurfadila Fani

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引用次数: 0

摘要

颈动脉内膜-中膜厚度（cIMT）是动脉粥样硬化的早期标志，与心血管疾病的风险增加有关。由于铁积累、一氧化氮减少和脂质过氧化作用增加，地中海贫血的心血管风险增加也与内皮功能障碍有关。地中海贫血患者动脉粥样硬化标志物的研究结果不一致。

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Transfusion frequency, ferritin, and carotid intima media thickness in transfusion-dependent thalassemia patients.

Introduction: The carotid tunica intima-media thickness (cIMT) is an early marker of atherosclerosis and associated with an increased risk of cardiovascular diseases. Endothelial dysfunction also contributed with the increased cardiovascular risk in thalassemia caused by iron accumulation, reduced nitric oxide, and increased lipid peroxidation. Studies about atherosclerosis markers in thalassemia patients show inconsistent results.

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来源期刊

Folia medica Medicine-Medicine (all)

CiteScore

1.00

自引率

0.00%

发文量

121

审稿时长

5 weeks