Isoquinoline Quaternary Alkaloid (IQA) Nano-dressings: A Comprehensive Review on Design Strategies, Therapeutic Applications, and Advancements in Transdermal Delivery for Chronic Wound Management.

Introduction: Transdermal delivery systems and wound dressings are critical components of modern healthcare, continually undergoing refinement to enhance efficacy, biocompatibility, and cost-effectiveness. Natural compounds, particularly those sourced from plants, have emerged as promising candidates for advancing these systems.

Aim and objective: This study aims to investigate the design, therapeutic potentials, and comparative advancements of Isoquinoline Quaternary Alkaloid (IQA) nano-dressings.

Materials and methods: The paper offers a comprehensive analysis of IQA's therapeutic potentials, fabrication techniques, and a comparative assessment against traditional wound care approaches, positioning IQA nano dressings as a paradigm shift in chronic wound management with the potential to enhance patient outcomes significantly.

Result: This review delves into the transformative capabilities of dissolving Isoquinoline Quaternary Alkaloid (IQA) nano dressings, showcasing their potential to revolutionize chronic wound care beyond conventional therapies.

Conclusion: Through the amalgamation of nanotechnology with IQA's intrinsic attributes, such as antimicrobial and anti-inflammatory properties, biocompatibility, and sustained drug release, these nanodressings exhibit promising outcomes in tissue regeneration while minimizing the need for frequent dressing changes.