{"title":"工程疫苗佐剂的技术与策略：综述","authors":"Suman Sharma, Rajani Chauhan, Qumar Negar, Pragya Sharma","doi":"10.2174/0115701638351666250405070745","DOIUrl":null,"url":null,"abstract":"<p><p>Vaccines are biological products used to prevent diseases and ailments caused by viruses, bacteria, and fungi. Vaccine adjuvants increase the potency of the vaccine. The vaccine adjuvants like gold nanoparticle, silver nanoparticle, Lentinan-calcium carbonate microsphere, Aluminium nano metal-organic framework, Poly[di(carboxylatomethylphenoxy)phosphazene] macromolecule, Lignin nanoparticle, Nanostructured hydroxy phosphate synthesized by Chemical and Biosynthesis and their evaluation method have been discussed. Evaluations for physical parameters like particle size and biological evaluation to find out the potency of adjuvants have been discussed. The adjuvant synthesis discussed is a potential method for improvement of the marketed vaccine.</p>","PeriodicalId":93962,"journal":{"name":"Current drug discovery technologies","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Techniques and Strategies for Engineering Vaccine Adjuvants: A Comprehensive Review.\",\"authors\":\"Suman Sharma, Rajani Chauhan, Qumar Negar, Pragya Sharma\",\"doi\":\"10.2174/0115701638351666250405070745\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Vaccines are biological products used to prevent diseases and ailments caused by viruses, bacteria, and fungi. Vaccine adjuvants increase the potency of the vaccine. The vaccine adjuvants like gold nanoparticle, silver nanoparticle, Lentinan-calcium carbonate microsphere, Aluminium nano metal-organic framework, Poly[di(carboxylatomethylphenoxy)phosphazene] macromolecule, Lignin nanoparticle, Nanostructured hydroxy phosphate synthesized by Chemical and Biosynthesis and their evaluation method have been discussed. Evaluations for physical parameters like particle size and biological evaluation to find out the potency of adjuvants have been discussed. The adjuvant synthesis discussed is a potential method for improvement of the marketed vaccine.</p>\",\"PeriodicalId\":93962,\"journal\":{\"name\":\"Current drug discovery technologies\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current drug discovery technologies\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/0115701638351666250405070745\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current drug discovery technologies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/0115701638351666250405070745","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Techniques and Strategies for Engineering Vaccine Adjuvants: A Comprehensive Review.
Vaccines are biological products used to prevent diseases and ailments caused by viruses, bacteria, and fungi. Vaccine adjuvants increase the potency of the vaccine. The vaccine adjuvants like gold nanoparticle, silver nanoparticle, Lentinan-calcium carbonate microsphere, Aluminium nano metal-organic framework, Poly[di(carboxylatomethylphenoxy)phosphazene] macromolecule, Lignin nanoparticle, Nanostructured hydroxy phosphate synthesized by Chemical and Biosynthesis and their evaluation method have been discussed. Evaluations for physical parameters like particle size and biological evaluation to find out the potency of adjuvants have been discussed. The adjuvant synthesis discussed is a potential method for improvement of the marketed vaccine.
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