The Use of Ablative Nonfractional CO2 Laser for the Treatment of Periocular Lesions: A Retrospective Study.

Background: In the eyelid region numerous lesions can develop, spanning from cosmetic imperfections to benign tumors and extending to inflammatory and precancerous lesions. Aim: This study aimed to treat benign periocular lesions with a CO₂ laser and assess the effectiveness, the number of sessions required for resolution, and any potential side effects after the procedure. Materials and Methods: All patients were treated with a nonfractional ablative CO₂ laser. The last evaluation and follow-up visit took place 2 months after the previous operation, with the clinical goal being the complete removal of the lesion. Before the first session and immediately afterward, clinical photographic documentation was completed, and it was done again 2 months after the final session. Patients were rated on a 4-point scale: none, mild, moderate, or severe. Results: A total of 715 patients were registered with different palpebral pathologies, all of whom showed good to excellent results with either no or mild adverse reactions. Conclusions: CO₂ laser is effective and well tolerated to treat periocular lesions, despite the sensitivity of this region.