{"title":"2型糖尿病与饮食抗氧化指数之间的关系：伊朗人群的横断面研究","authors":"Zahra Roumi, Majid Kamali, Masoomeh Alsadat Mirshafaei, Saheb Abbas Torki, Bahareh Aminnezhad, Zahra Mahmoudi, Soheila Shekari, Ali Shamsi-Goushki, Kadijeh Abbasi Mobarakeh, Masoomeh Ataei Kachooei, Maryam Gholamalizadeh, Saeed Omidi, Parsa Bahmani, Saeid Doaei, Hamideh YazdiMoghaddam","doi":"10.20945/2359-4292-2024-0170","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study aims to explore the association between dietary antioxidant index (DAI) and type 2 diabetes (T2D) in the Iranian population.</p><p><strong>Subjects and methods: </strong>The present cross- sectional study comprised 4,241 participants aged from 35 to 70. A food frequency questionnaire (FFQ) was used to assess dietary intake. The DAI score was determined using Wright's method, which quantifies the antioxidant content of the diet. Logistic and linear regression analyses were used to determine the link between DAI and T2D after adjusting for confounding variables.</p><p><strong>Results: </strong>Negative associations were found between T2D with total score of DAI (OR = 0.67, CI95%: 0.55-0.81, P = 0.001) and DAI score of zinc (OR = 0.53, CI95%: 0.40-0.72, P = 0.001), manganese (OR = 0.77, CI95%: 0.68-0.88, P = 0.001), and selenium (OR = 0.88, CI95%: 0.78-0.98, P = 0.010) after adjustments for age, sex, BMI, education level, marital status, occupation, physical activity, and calorie intake.</p><p><strong>Conclusion: </strong>These results indicate the significance of an antioxidant-rich diet in preventing T2D and its complications. Nevertheless, additional investigation is required to validate these findings and explore the fundamental mechanisms of the association of T2D and dietary antioxidants.</p>","PeriodicalId":54303,"journal":{"name":"Archives of Endocrinology Metabolism","volume":"68 ","pages":"e240170"},"PeriodicalIF":1.6000,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967183/pdf/","citationCount":"0","resultStr":"{\"title\":\"The association between type 2 diabetes and dietary antioxidant index: a cross-sectional study in the Iranian population.\",\"authors\":\"Zahra Roumi, Majid Kamali, Masoomeh Alsadat Mirshafaei, Saheb Abbas Torki, Bahareh Aminnezhad, Zahra Mahmoudi, Soheila Shekari, Ali Shamsi-Goushki, Kadijeh Abbasi Mobarakeh, Masoomeh Ataei Kachooei, Maryam Gholamalizadeh, Saeed Omidi, Parsa Bahmani, Saeid Doaei, Hamideh YazdiMoghaddam\",\"doi\":\"10.20945/2359-4292-2024-0170\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>This study aims to explore the association between dietary antioxidant index (DAI) and type 2 diabetes (T2D) in the Iranian population.</p><p><strong>Subjects and methods: </strong>The present cross- sectional study comprised 4,241 participants aged from 35 to 70. A food frequency questionnaire (FFQ) was used to assess dietary intake. The DAI score was determined using Wright's method, which quantifies the antioxidant content of the diet. Logistic and linear regression analyses were used to determine the link between DAI and T2D after adjusting for confounding variables.</p><p><strong>Results: </strong>Negative associations were found between T2D with total score of DAI (OR = 0.67, CI95%: 0.55-0.81, P = 0.001) and DAI score of zinc (OR = 0.53, CI95%: 0.40-0.72, P = 0.001), manganese (OR = 0.77, CI95%: 0.68-0.88, P = 0.001), and selenium (OR = 0.88, CI95%: 0.78-0.98, P = 0.010) after adjustments for age, sex, BMI, education level, marital status, occupation, physical activity, and calorie intake.</p><p><strong>Conclusion: </strong>These results indicate the significance of an antioxidant-rich diet in preventing T2D and its complications. 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引用次数: 0
摘要
目的：本研究旨在探讨伊朗人群饮食抗氧化指数（DAI）与2型糖尿病（T2D）之间的关系。对象与方法：本横断面研究包括4,241名年龄在35岁至70岁之间的参与者。采用食物频率问卷（FFQ）评估膳食摄入量。DAI评分采用赖特的方法确定，该方法量化了饮食中的抗氧化剂含量。在调整混杂变量后，采用Logistic和线性回归分析来确定DAI与T2D之间的联系。结果：调整年龄、性别、BMI、受教育程度、婚姻状况、职业、体力活动、热量摄入等因素后，T2D与DAI总分（OR = 0.67, CI95%: 0.55 ~ 0.81, P = 0.001）、锌（OR = 0.53, CI95%: 0.40 ~ 0.72, P = 0.001）、锰（OR = 0.77, CI95%: 0.68 ~ 0.88, P = 0.010）、硒（OR = 0.88, CI95%: 0.78 ~ 0.98, P = 0.010）呈负相关。结论：提示富抗氧化剂饮食对预防t2dm及其并发症的重要意义。然而，需要进一步的研究来验证这些发现，并探索T2D和膳食抗氧化剂之间关系的基本机制。
The association between type 2 diabetes and dietary antioxidant index: a cross-sectional study in the Iranian population.
Objective: This study aims to explore the association between dietary antioxidant index (DAI) and type 2 diabetes (T2D) in the Iranian population.
Subjects and methods: The present cross- sectional study comprised 4,241 participants aged from 35 to 70. A food frequency questionnaire (FFQ) was used to assess dietary intake. The DAI score was determined using Wright's method, which quantifies the antioxidant content of the diet. Logistic and linear regression analyses were used to determine the link between DAI and T2D after adjusting for confounding variables.
Results: Negative associations were found between T2D with total score of DAI (OR = 0.67, CI95%: 0.55-0.81, P = 0.001) and DAI score of zinc (OR = 0.53, CI95%: 0.40-0.72, P = 0.001), manganese (OR = 0.77, CI95%: 0.68-0.88, P = 0.001), and selenium (OR = 0.88, CI95%: 0.78-0.98, P = 0.010) after adjustments for age, sex, BMI, education level, marital status, occupation, physical activity, and calorie intake.
Conclusion: These results indicate the significance of an antioxidant-rich diet in preventing T2D and its complications. Nevertheless, additional investigation is required to validate these findings and explore the fundamental mechanisms of the association of T2D and dietary antioxidants.
期刊介绍：
The Archives of Endocrinology and Metabolism - AE&M – is the official journal of the Brazilian Society of Endocrinology and Metabolism - SBEM, which is affiliated with the Brazilian Medical Association.
Edited since 1951, the AE&M aims at publishing articles on scientific themes in the basic translational and clinical area of Endocrinology and Metabolism. The printed version AE&M is published in 6 issues/year. The full electronic issue is open access in the SciELO - Scientific Electronic Library Online e at the AE&M site: www.aem-sbem.com.
From volume 59 on, the name was changed to Archives of Endocrinology and Metabolism, and it became mandatory for manuscripts to be submitted in English for the online issue. However, for the printed issue it is still optional for the articles to be sent in English or Portuguese.
The journal is published six times a year, with one issue every two months.
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