Myelomatous pleural effusion: An atypical initial presentation.

Abstract: Malignant pleural effusion is usually due to metastatic involvement of the pleura from primary malignancies of the lung, breast, ovaries, sarcoma, lymphomas and mesothelioma. Pleural effusion as an initial presentation of multiple myeloma (MM) is extremely rare (<1%) and is associated with a poor prognosis. Here, we present a case of a 50-year-old male who presented with unilateral massive pleural effusion, lung mass, renal failure and anaemia secondary to MM.