{"title":"生活方式行为减肥治疗肥胖患者暴食症:危害在哪里?","authors":"Sydney Yurkow, Valentina Ivezaj, Carlos M. Grilo","doi":"10.1002/oby.24289","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objective</h3>\n \n <p>Although recent rigorous trials have demonstrated effectiveness of behaviorally based weight-loss treatment (BBWLT) for binge-eating disorder (BED) with coexisting obesity, concerns have been raised that such interventions are contraindicated because they might trigger or exacerbate eating disorder (ED) psychopathology. This secondary analysis of a BBWLT trial examined heterogeneity of outcomes to identify the frequency that individuals experienced increased symptoms.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>One hundred ninety-one participants with BED and obesity in a 6-month BBWLT trial were assessed for binge eating, ED psychopathology, and weight at baseline, at posttreatment, and at a 12-month follow-up after treatment (i.e., 18 months after baseline). Changes were examined at the individual level to identify cases of any increased features.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>At posttreatment, 95.3% (<i>n</i> = 162) of participants reported decreased binge-eating frequency, and 87.6% (<i>n</i> = 149) reported decreased ED psychopathology scores. At the 12-month follow-up, 97.1% (<i>n</i> = 135) reported decreased binge-eating frequency, and 93.0% (<i>n</i> = 120) reported decreased ED psychopathology scores. Inspection of the few instances of any increases revealed mostly small magnitudes.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>Frequency of cases with any increased symptoms of binge eating and/or ED psychopathology was quite low at posttreatment and at 1 year after ending BBWLT for BED and obesity. These participant-level findings add important clinical context regarding overall improvements with BBWLT for BED with obesity (large effect sizes) and challenge concerns that BBWLT exacerbates ED psychopathology.</p>\n </section>\n </div>","PeriodicalId":215,"journal":{"name":"Obesity","volume":"33 6","pages":"1058-1066"},"PeriodicalIF":4.7000,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/oby.24289","citationCount":"0","resultStr":"{\"title\":\"Lifestyle behavioral weight-loss treatment for binge-eating disorder in patients with obesity: where's the harm?\",\"authors\":\"Sydney Yurkow, Valentina Ivezaj, Carlos M. Grilo\",\"doi\":\"10.1002/oby.24289\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objective</h3>\\n \\n <p>Although recent rigorous trials have demonstrated effectiveness of behaviorally based weight-loss treatment (BBWLT) for binge-eating disorder (BED) with coexisting obesity, concerns have been raised that such interventions are contraindicated because they might trigger or exacerbate eating disorder (ED) psychopathology. This secondary analysis of a BBWLT trial examined heterogeneity of outcomes to identify the frequency that individuals experienced increased symptoms.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>One hundred ninety-one participants with BED and obesity in a 6-month BBWLT trial were assessed for binge eating, ED psychopathology, and weight at baseline, at posttreatment, and at a 12-month follow-up after treatment (i.e., 18 months after baseline). Changes were examined at the individual level to identify cases of any increased features.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>At posttreatment, 95.3% (<i>n</i> = 162) of participants reported decreased binge-eating frequency, and 87.6% (<i>n</i> = 149) reported decreased ED psychopathology scores. At the 12-month follow-up, 97.1% (<i>n</i> = 135) reported decreased binge-eating frequency, and 93.0% (<i>n</i> = 120) reported decreased ED psychopathology scores. Inspection of the few instances of any increases revealed mostly small magnitudes.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>Frequency of cases with any increased symptoms of binge eating and/or ED psychopathology was quite low at posttreatment and at 1 year after ending BBWLT for BED and obesity. These participant-level findings add important clinical context regarding overall improvements with BBWLT for BED with obesity (large effect sizes) and challenge concerns that BBWLT exacerbates ED psychopathology.</p>\\n </section>\\n </div>\",\"PeriodicalId\":215,\"journal\":{\"name\":\"Obesity\",\"volume\":\"33 6\",\"pages\":\"1058-1066\"},\"PeriodicalIF\":4.7000,\"publicationDate\":\"2025-05-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/oby.24289\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Obesity\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/oby.24289\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Obesity","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/oby.24289","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
Lifestyle behavioral weight-loss treatment for binge-eating disorder in patients with obesity: where's the harm?
Objective
Although recent rigorous trials have demonstrated effectiveness of behaviorally based weight-loss treatment (BBWLT) for binge-eating disorder (BED) with coexisting obesity, concerns have been raised that such interventions are contraindicated because they might trigger or exacerbate eating disorder (ED) psychopathology. This secondary analysis of a BBWLT trial examined heterogeneity of outcomes to identify the frequency that individuals experienced increased symptoms.
Methods
One hundred ninety-one participants with BED and obesity in a 6-month BBWLT trial were assessed for binge eating, ED psychopathology, and weight at baseline, at posttreatment, and at a 12-month follow-up after treatment (i.e., 18 months after baseline). Changes were examined at the individual level to identify cases of any increased features.
Results
At posttreatment, 95.3% (n = 162) of participants reported decreased binge-eating frequency, and 87.6% (n = 149) reported decreased ED psychopathology scores. At the 12-month follow-up, 97.1% (n = 135) reported decreased binge-eating frequency, and 93.0% (n = 120) reported decreased ED psychopathology scores. Inspection of the few instances of any increases revealed mostly small magnitudes.
Conclusions
Frequency of cases with any increased symptoms of binge eating and/or ED psychopathology was quite low at posttreatment and at 1 year after ending BBWLT for BED and obesity. These participant-level findings add important clinical context regarding overall improvements with BBWLT for BED with obesity (large effect sizes) and challenge concerns that BBWLT exacerbates ED psychopathology.
期刊介绍:
Obesity is the official journal of The Obesity Society and is the premier source of information for increasing knowledge, fostering translational research from basic to population science, and promoting better treatment for people with obesity. Obesity publishes important peer-reviewed research and cutting-edge reviews, commentaries, and public health and medical developments.