鞍上区青少年毛细胞星形细胞瘤11例的MR影像特征分析。

IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Xiaocai Zhang, Hongyue Tao, Zhenqing Liu, Zidong Zhou, Li Huang, Guangbi Song
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引用次数: 0

摘要

目的:本研究旨在描述11例儿童鞍上毛细胞星形细胞瘤(PA)的磁共振成像(MRI)表现,帮助神经放射学家术前区分PA与其他鞍上肿瘤。方法:选取2015年5月至2021年11月我院连续11例经病理证实的鞍上PAs患儿为研究对象。回顾性分析临床资料及术前MR图像。MRI包括t1加权成像(T1WI)、t2加权成像(T2WI)、液体衰减反转恢复(FLAIR)和对比后T1WI。6例患者行弥散加权成像(DWI)。评估病变的MRI位置、信号特征、增强模式及表观扩散系数(ADC)。记录患者术后3年的临床情况。结果:11个鞍上PAs主要位于视交叉和下丘脑周围,侵犯邻近结构。T2WI呈高或轻度高信号,T1WI呈低信号。11例患者中,均质强化的实体瘤5例,非均质强化的实体瘤1例,非均质强化的囊性和实体瘤5例。4例患者出现脑脊液传播灶。病变实性成分DWI呈低或等强度,ADC值高,平均为1.77±0.36 ×10-3 mm2/s。只有1例(9.1%)患者实现了大体全切除,10例(90.9%)患者实现了部分全切除。随访期间死亡5例,3年生存率为54.5%。结论:青少年鞍上PAs表现为实性及囊实混合征,T2W高影,实性成分增强明显,ADC值较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
MR Imaging Features of Juvenile Pilocytic Astrocytoma in the Suprasellar Region: A Study on 11 Patients.

Objective: This study aimed to characterize the magnetic resonance imaging (MRI) findings of juvenile suprasellar pilocytic astrocytoma (PA) in a sample of 11 children and help neuroradiologists preoperatively differentiate PAs from other suprasellar tumors.

Methods: Eleven consecutive children with pathologically confirmed suprasellar PAs in our hospital from May 2015 to November 2021 were enrolled in this study. The clinical data and preoperative MR images were retrospectively reviewed. MRI included T1-weighted imaging (T1WI), T2-weighted imaging (T2WI), fluid-attenuated inversion recovery (FLAIR), and postcontrast T1WI. Six patients underwent diffusion-weighted imaging (DWI). The location, signal features, enhancement pattern, and apparent diffusion coefficient (ADC) of the lesions on MRI were evaluated. The clinical status of the patients 3 years after surgery was noted.

Results: The 11 suprasellar PAs were mainly located around the optic chiasma and hypothalamus and invaded adjacent structures. The lesions showed hyperintensity or slight hyperintensity on T2WI and hypointensity on T1WI. Among the 11 patients, 5 had solid tumors with homogeneous enhancement, one had a solid tumor with heterogeneous enhancement, and five had cystic and solid tumors with heterogeneous enhancement. Cerebrospinal fluid (CSF) dissemination foci were observed in 4 patients. The solid components of the lesions were hypointense or isointense on DWI, with high ADC values at a mean of 1.77±0.36 ×10-3 mm2/s. Gross total resection was achieved in only one patient (9.1%), and 10 (90.9%) were subtotally resected. Five patients died during the follow-up period, and the 3-year survival rate was 54.5%.

Conclusion: Juvenile suprasellar PAs are characterized by a solid and intermixed cystic and solid appearance, hyperintensity on T2W images, obvious enhancement of the solid component, and relatively high ADC values.

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来源期刊
CiteScore
2.60
自引率
0.00%
发文量
246
审稿时长
1 months
期刊介绍: Current Medical Imaging Reviews publishes frontier review articles, original research articles, drug clinical trial studies and guest edited thematic issues on all the latest advances on medical imaging dedicated to clinical research. All relevant areas are covered by the journal, including advances in the diagnosis, instrumentation and therapeutic applications related to all modern medical imaging techniques. The journal is essential reading for all clinicians and researchers involved in medical imaging and diagnosis.
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