{"title":"人类动脉粥样硬化斑块的三级淋巴器官。","authors":"Devadatta Gosavi, Klaus Ley","doi":"10.1038/s44161-025-00645-x","DOIUrl":null,"url":null,"abstract":"The discovery of plaque tertiary lymphoid organs (PTLOs) within human atherosclerotic plaques provides insights into the role of the immune system in atherosclerosis. The findings highlight the cellular and molecular features of PTLOs, and suggest a potential role of PTLOs in driving plaque instability by activating adaptive immune responses.","PeriodicalId":74245,"journal":{"name":"Nature cardiovascular research","volume":"4 5","pages":"500-502"},"PeriodicalIF":10.8000,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Tertiary lymphoid organs in human atherosclerotic plaques\",\"authors\":\"Devadatta Gosavi, Klaus Ley\",\"doi\":\"10.1038/s44161-025-00645-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The discovery of plaque tertiary lymphoid organs (PTLOs) within human atherosclerotic plaques provides insights into the role of the immune system in atherosclerosis. The findings highlight the cellular and molecular features of PTLOs, and suggest a potential role of PTLOs in driving plaque instability by activating adaptive immune responses.\",\"PeriodicalId\":74245,\"journal\":{\"name\":\"Nature cardiovascular research\",\"volume\":\"4 5\",\"pages\":\"500-502\"},\"PeriodicalIF\":10.8000,\"publicationDate\":\"2025-04-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature cardiovascular research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s44161-025-00645-x\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature cardiovascular research","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44161-025-00645-x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Tertiary lymphoid organs in human atherosclerotic plaques
The discovery of plaque tertiary lymphoid organs (PTLOs) within human atherosclerotic plaques provides insights into the role of the immune system in atherosclerosis. The findings highlight the cellular and molecular features of PTLOs, and suggest a potential role of PTLOs in driving plaque instability by activating adaptive immune responses.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
