Ngoc Can Thi Bich, Son Do Tien, Khanh Nguyen Ngoc, Dien Tran Minh, Bach Le Xuan, Xuan Bui Thi, Huong Bui Thi, Linh Tran Thi Thuy, Hoa Do Thi, Huong Nguyen Thi Thu, Thao Bui Phuong, Dung Vu Chi
{"title":"越南第三儿科中心新诊断1型糖尿病的发病率和特点：早期发现的挑战","authors":"Ngoc Can Thi Bich, Son Do Tien, Khanh Nguyen Ngoc, Dien Tran Minh, Bach Le Xuan, Xuan Bui Thi, Huong Bui Thi, Linh Tran Thi Thuy, Hoa Do Thi, Huong Nguyen Thi Thu, Thao Bui Phuong, Dung Vu Chi","doi":"10.6065/apem.2448282.141","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to estimate the incidence and examine the clinical and laboratory characteristics of newly diagnosed Type 1 Diabetes (T1D) in Vietnamese children at a tertiary referral pediatric hospital.</p><p><strong>Methods: </strong>A retrospective cross-sectional analysis was conducted on 64 children newly diagnosed with T1D at the Vietnam National Children Hospital in 2023. Data on the children were analysed, including demographics, family history, symptoms, anthropometric measurements, HbA1c levels, and pancreatic islet autoantibodies.</p><p><strong>Results: </strong>The average age at diagnosis was 9.1±3.7 years, with a male predominance (53.1%). The incidence Rate of T1D was 0.77 per 100,000 children in Northern Vietnam. Diabetic ketoacidosis (DKA) was present in 57.8% of children at diagnosis, and 75% tested positive for autoantibodies. The Red River Delta reported the highest children with T1D proportion (43.5%), but the incident rate was highest in Hanoi capital (0.91 per 100,000 children).</p><p><strong>Conclusions: </strong>This study underscores the considerable diagnostic delays in type 1 diabetes (T1D) in a tertiary pediatric centre in Vietnam, with a high prevalence of diabetic ketoacidosis. The results highlight the urgent need for an enhanced network of satellite hospitals to enable early diagnosis and treatment for patients.</p>","PeriodicalId":44915,"journal":{"name":"Annals of Pediatric Endocrinology & Metabolism","volume":" ","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Incidence rate and characteristics of newly diagnosed type 1 diabetes in Vietnam tertiary pediatric center: challenges in early detection.\",\"authors\":\"Ngoc Can Thi Bich, Son Do Tien, Khanh Nguyen Ngoc, Dien Tran Minh, Bach Le Xuan, Xuan Bui Thi, Huong Bui Thi, Linh Tran Thi Thuy, Hoa Do Thi, Huong Nguyen Thi Thu, Thao Bui Phuong, Dung Vu Chi\",\"doi\":\"10.6065/apem.2448282.141\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>This study aims to estimate the incidence and examine the clinical and laboratory characteristics of newly diagnosed Type 1 Diabetes (T1D) in Vietnamese children at a tertiary referral pediatric hospital.</p><p><strong>Methods: </strong>A retrospective cross-sectional analysis was conducted on 64 children newly diagnosed with T1D at the Vietnam National Children Hospital in 2023. Data on the children were analysed, including demographics, family history, symptoms, anthropometric measurements, HbA1c levels, and pancreatic islet autoantibodies.</p><p><strong>Results: </strong>The average age at diagnosis was 9.1±3.7 years, with a male predominance (53.1%). The incidence Rate of T1D was 0.77 per 100,000 children in Northern Vietnam. Diabetic ketoacidosis (DKA) was present in 57.8% of children at diagnosis, and 75% tested positive for autoantibodies. The Red River Delta reported the highest children with T1D proportion (43.5%), but the incident rate was highest in Hanoi capital (0.91 per 100,000 children).</p><p><strong>Conclusions: </strong>This study underscores the considerable diagnostic delays in type 1 diabetes (T1D) in a tertiary pediatric centre in Vietnam, with a high prevalence of diabetic ketoacidosis. The results highlight the urgent need for an enhanced network of satellite hospitals to enable early diagnosis and treatment for patients.</p>\",\"PeriodicalId\":44915,\"journal\":{\"name\":\"Annals of Pediatric Endocrinology & Metabolism\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-05-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Pediatric Endocrinology & Metabolism\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.6065/apem.2448282.141\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Pediatric Endocrinology & Metabolism","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6065/apem.2448282.141","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
Incidence rate and characteristics of newly diagnosed type 1 diabetes in Vietnam tertiary pediatric center: challenges in early detection.
Purpose: This study aims to estimate the incidence and examine the clinical and laboratory characteristics of newly diagnosed Type 1 Diabetes (T1D) in Vietnamese children at a tertiary referral pediatric hospital.
Methods: A retrospective cross-sectional analysis was conducted on 64 children newly diagnosed with T1D at the Vietnam National Children Hospital in 2023. Data on the children were analysed, including demographics, family history, symptoms, anthropometric measurements, HbA1c levels, and pancreatic islet autoantibodies.
Results: The average age at diagnosis was 9.1±3.7 years, with a male predominance (53.1%). The incidence Rate of T1D was 0.77 per 100,000 children in Northern Vietnam. Diabetic ketoacidosis (DKA) was present in 57.8% of children at diagnosis, and 75% tested positive for autoantibodies. The Red River Delta reported the highest children with T1D proportion (43.5%), but the incident rate was highest in Hanoi capital (0.91 per 100,000 children).
Conclusions: This study underscores the considerable diagnostic delays in type 1 diabetes (T1D) in a tertiary pediatric centre in Vietnam, with a high prevalence of diabetic ketoacidosis. The results highlight the urgent need for an enhanced network of satellite hospitals to enable early diagnosis and treatment for patients.
期刊介绍：
The Annals of Pediatric Endocrinology & Metabolism Journal is the official publication of the Korean Society of Pediatric Endocrinology. Its formal abbreviated title is “Ann Pediatr Endocrinol Metab”. It is a peer-reviewed open access journal of medicine published in English. The journal was launched in 1996 under the title of ‘Journal of Korean Society of Pediatric Endocrinology’ until 2011 (pISSN 1226-2242). Since 2012, the title is now changed to ‘Annals of Pediatric Endocrinology & Metabolism’. The Journal is published four times per year on the last day of March, June, September, and December. It is widely distributed for free to members of the Korean Society of Pediatric Endocrinology, medical schools, libraries, and academic institutions. The journal is indexed/tracked/covered by web sites of PubMed Central, PubMed, Emerging Sources Citation Index (ESCI), Scopus, EBSCO, EMBASE, KoreaMed, KoMCI, KCI, Science Central, DOI/CrossRef, Directory of Open Access Journals(DOAJ), and Google Scholar. The aims of Annals of Pediatric Endocrinology & Metabolism are to contribute to the advancements in the fields of pediatric endocrinology & metabolism through the scientific reviews and interchange of all of pediatric endocrinology and metabolism. It aims to reflect the latest clinical, translational, and basic research trends from worldwide valuable achievements. In addition, genome research, epidemiology, public education and clinical practice guidelines in each country are welcomed for publication. The Journal particularly focuses on research conducted with Asian-Pacific children whose genetic and environmental backgrounds are different from those of the Western. Area of specific interest include the following : Growth, puberty, glucose metabolism including diabetes mellitus, obesity, nutrition, disorders of sexual development, pituitary, thyroid, parathyroid, adrenal cortex, bone or other endocrine and metabolic disorders from infancy through adolescence.
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