超越疾病的分枝杆菌。

IF 14 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Trends in Microbiology Pub Date : 2025-04-28 DOI:10.1016/j.tim.2025.04.008

Terence K Tutumlu, Cédric Dollé, Katharina Kusejko, Sébastien Gagneux, Silvio D Brugger, Huldrych F Günthard, Johannes Nemeth

引用次数: 0

摘要

分枝杆菌与人类共同进化了几千年，在我们的免疫系统上留下了深刻的印记。除了活动性疾病外，它们的暴露还可能发挥免疫调节作用，包括过敏调节和对感染的异源保护。这篇论坛文章探讨了这些潜在的相互作用，强调了它们在新疗法和公共卫生策略方面的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Mycobacteria beyond disease.

Mycobacteria have coevolved with humans over millennia, leaving profound imprints on our immune systems. Beyond active disease, their exposure may exert immunomodulatory effects, including allergy modulation and heterologous protection against infections. This forum article explores these potentially mutualistic interactions, highlighting their potential for novel therapies and public health strategies.

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来源期刊

Trends in Microbiology 生物-生化与分子生物学

CiteScore

25.30

自引率

0.60%

发文量

193

审稿时长

6-12 weeks

期刊介绍： Trends in Microbiology serves as a comprehensive, multidisciplinary forum for discussing various aspects of microbiology, spanning cell biology, immunology, genetics, evolution, virology, bacteriology, protozoology, and mycology. In the rapidly evolving field of microbiology, technological advancements, especially in genome sequencing, impact prokaryote biology from pathogens to extremophiles, influencing developments in drugs, vaccines, and industrial enzyme research.