Exploring the potential of Rosa chinensis, Rosa cymosa, and Rosa indica in oral disease prevention: A multifaceted approach.

Introduction: Rose species that are well-known for their therapeutic qualities include Rosa chinensis, Rosa cymosa, and Rosa indica. The study employs in vitro assays and in silico molecular docking to investigate their phytochemical composition and antioxidant properties.

Methods: Phytochemicals were detected in flower petals of Rosa chinensis, Rosa cymosa, and Rosa indica that had been extracted using methanol. Ascorbic acid was utilised as the standard reference for assessing antioxidant activity and its hydrogen peroxide scavenging potential. Superoxide dismutase (SOD) interactions with berberine, emodin, and limonene were assessed by molecular docking using PyRx software.

Results: Various beneficial substances were found in all species according to phytochemical investigation. Among the three Rosa species, R. chinensis demonstrated the highest antioxidant activity, followed by R. cymosa and R. indica. Docking studies demonstrated that berberine and emodin had substantial binding affinity with SOD. The extracts showed strong antioxidant properties, suggesting that they could be used as naturally occurring antioxidants.

Conclusions: Rosa chinensis, Rosa cymosa, and Rosa indica show promise as medicinal plants and have strong antioxidant properties. The results validate the development of these rose species as naturally occurring antioxidants for the treatment of ailments related with oxidative stress.