慢性炎症性风湿病与女性生育能力。

IF 0.6 4区 医学 Q4 OBSTETRICS & GYNECOLOGY
Mathilde Bourdon, Camille Artru, Anna Molto, Mathilde Barrois, Chloé Maignien, Catherine Patrat, Charles Chapron, Pietro Santulli
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引用次数: 0

摘要

慢性炎症性风湿病(CIRDs)是一组引起炎症性关节疼痛的疾病,可影响渴望怀孕的年轻女性。cird可以影响女性的生育能力,尽管确切的影响尚不完全清楚。一些研究报告生育能力下降,特别是由于长期的受孕延迟,这与多种因素有关。其中,由于疼痛和慢性疲劳,性功能障碍是常见的。cird对卵巢储备的影响仍有争议。关于治疗,疾病缓解药物没有显示出对生育的有害影响,但某些致畸治疗应避免希望怀孕的妇女。此外,cird似乎与一些已知不育原因的妇科疾病有关。对于cird患者,早期讨论生育是必要的。在希望怀孕的情况下,孕前咨询对于调整治疗、管理风险和在最佳条件下为怀孕做准备是必不可少的。在确诊不孕症的情况下,辅助生殖技术是一种治疗选择。一些研究表明,成功率可能低于在普通人群中观察到的成功率。包括风湿病学家、妇科医生和生殖专家在内的多学科方法,以及孕前期的治疗优化,对于提高受孕机会和为这些患者提供适当的随访至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Chronic inflammatory rheumatic diseases and female fertility].

Chronic inflammatory rheumatic diseases (CIRDs) are a group of diseases responsible for inflammatory joint pains and can affect young women with a desire to conceive. CIRDs can impact female fertility, although the exact effects are still not fully understood. Some studies report reduced fertility, particularly due to prolonged conception delays, which are related to multiple factors. Among these, sexual dysfunction is common due to pain and chronic fatigue. The impact of CIRDs on ovarian reserve remains controversial. Regarding treatments, disease-modifying drugs have not shown a deleterious effect on fertility, but certain teratogenic treatments should be avoided in women who wish to conceive. Furthermore, there appears to be an association between CIRDs and some gynecological conditions known causes of infertility. For patients with CIRDs, early discussion about fertility is necessary. In the case of a desire for pregnancy, preconception consultation is essential to adjust treatments, manage risks, and prepare for pregnancy under the best possible conditions. In cases of proven infertility, assisted reproductive technology is a therapeutic option. Some studies suggest that success rates may be lower than those observed in the general population. A multidisciplinary approach involving rheumatologists, gynecologists, and reproductive specialists, as well as therapeutic optimization during the preconception period, is crucial to improve the chances of conception and provide appropriate follow-up for these patients.

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来源期刊
Gynecologie Obstetrique Fertilite & Senologie
Gynecologie Obstetrique Fertilite & Senologie Medicine-Obstetrics and Gynecology
CiteScore
1.70
自引率
0.00%
发文量
170
期刊介绍: Gynécologie Obstétrique Fertilité & Sénologie est un mensuel scientifique d''information et de formation destiné aux gynécologues, aux obstétriciens, aux sénologues et aux biologistes de la reproduction. La revue, dans ses éditoriaux, articles originaux, mises au point, lettres à la rédaction et autres rubriques, donne une information actualisée ayant trait à l''obstétrique et à la gynécologie et aux différentes spécialités développées à partir de ces deux pôles : médecine de la reproduction, médecine maternelle et fœtale, périnatalité, endocrinologie, chirurgie gynécologique, cancérologie pelvienne, sénologie, sexualité, psychosomatique…
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