新形成的骨与感染和非感染牙齿是否保留牙槽嵴的实验性种植周炎进展之间的相关性:临床前研究的二次分析

IF 2.2 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE
Jungwoo Jung, Seunghee Lee, Jungwon Lee, Young-Chang Ko, Dongseob Lee, Yang-Jo Seol, Ki-Tae Koo, Yong-Moo Lee
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引用次数: 0

摘要

目的:我们研究了实验性种植体周围炎在接受牙槽嵴保存(ARP)或自发愈合(SH)的部位的进展,比较了感染牙齿(IT)和未感染牙齿(NIT)。本研究是对一项临床前研究的二次分析,旨在探讨新形成的骨与种植体稳定商(ISQ)之间的关系,以及新形成的骨与实验性种植体周围炎进展之间的关系。方法:将6只beagle犬双侧下颌第三或第四前磨牙随机分为IT/SH、IT/ARP、NIT/SH、NIT/ARP 4组。植入后,从每个部位取芯活检,并测量ISQ值。植入体周围炎诱导期为3个月,植入体周围炎自发进展期为3个月,在每个时间点拍摄x线片。结果:在种植体周围炎自发进展过程中,各组间平均ISQ值和x线边缘骨丢失无统计学差异。同样,在核心活检中,骨替代品、新形成的骨和纤维血管结缔组织的百分比在各组之间没有显著差异。线性回归分析显示,各组新生骨与ISQ无显著线性相关(P < 0.05)。然而,仅在IT/SH组中,种植体周围炎自发进展期间新形成的骨与边缘骨丢失之间存在弱线性相关(P=0.036)。结论:在本研究的限制下,我们无法证明ARP可以改善新骨或初级种植体的稳定性。此外,ARP和SH均未显著影响实验性种植体周围炎的自发进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Correlation between newly formed bone and the progression of experimental peri-implantitis with or without alveolar ridge preservation in infected and non-infected teeth: a secondary analysis of a preclinical study.

Purpose: We examined the progression of experimental peri-implantitis in sites that underwent either alveolar ridge preservation (ARP) or spontaneous healing (SH), comparing infected teeth (IT) and non-infected teeth (NIT). This investigation is a secondary analysis of a preclinical study aimed at exploring the correlation between newly formed bone and implant stability quotient (ISQ), as well as the association between newly formed bone and the progression of experimental peri-implantitis.

Methods: The bilateral mandibular third or fourth premolars of 6 beagle dogs were randomly assigned to 4 groups: IT/SH, IT/ARP, NIT/SH, and NIT/ARP. Following implant placement, core biopsies were retrieved from each site, and the ISQ value was measured. A 3-month period was allowed for peri-implantitis induction, followed by an additional 3 months for the spontaneous progression of peri-implantitis, with radiographs taken at each time point.

Results: During the spontaneous progression of peri-implantitis, no statistically significant differences were observed among the groups in terms of mean ISQ values and radiographic marginal bone loss. Similarly, the percentages of bone substitute, newly formed bone, and fibrovascular connective tissue in core biopsies did not differ significantly among the groups. Linear regression analysis revealed no significant linear correlation between newly formed bone and ISQ in any group (P>0.05). However, a weak linear correlation between newly formed bone and marginal bone loss during the spontaneous progression of peri-implantitis was noted in the IT/SH group alone (P=0.036).

Conclusions: Within the limitations of this study, we were unable to demonstrate that ARP could improve newly formed bone or primary implant stability. Furthermore, neither ARP nor SH significantly influenced the spontaneous progression of experimental peri-implantitis.

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来源期刊
Journal of Periodontal and Implant Science
Journal of Periodontal and Implant Science DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
3.30
自引率
5.30%
发文量
38
期刊介绍: Journal of Periodontal & Implant Science (JPIS) is a peer-reviewed and open-access journal providing up-to-date information relevant to professionalism of periodontology and dental implantology. JPIS is dedicated to global and extensive publication which includes evidence-based original articles, and fundamental reviews in order to cover a variety of interests in the field of periodontal as well as implant science.
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