椰子油作为驱蚊剂的潜力。

IF 3.6 Q1 TROPICAL MEDICINE
Shiho Hara, Micheal Teron Pillay, Toshihiko Sunahara, Masaru Nagashima, Lucy Atieno Okech, Chiaki Tsurukawa, Yasuhiko Kamiya
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引用次数: 0

摘要

背景:除蚊帐和化学驱蚊剂外,天然衍生产品已成为一种流行的驱蚊剂。椰子衍生的脂肪酸已经证明了对各种吸血节肢动物(包括蚊子)的驱避特性。日常使用的含有椰子的润肤霜和身体皂对蚊子有一定的驱蚊效果。然而,没有专门对椰子油进行过研究,纯椰子油在肯尼亚西部地区的影响仍然未知。方法:本研究采用实验室和现场两种方法,对椰子油对蚊虫叮咬的减少效果进行了研究。以斯氏按蚊为实验对象,在一种haemtek供血装置上比较了椰子油处理膜和未处理膜。在肯尼亚西部的横断面研究中,我们调查了490名5岁及以下儿童的咬伤计数。采用描述性分析、简单回归、多元回归和混合回归模型。结果是蚊子叮咬痕迹的数量,除人口统计、环境、行为和社会经济变量外,主要解释变量是护肤霜类型。结果:椰子油显著降低了蚊子的采血率,合并Mantel-Haenszel优势比为0.06,Mantel-Haenszel卡方统计量为79.82 (p = 0.01),平均采血率为1%,对照组为31%。混合模型在考虑村级随机效应的同时,确定了影响蚊虫叮咬数的重要因素。与使用合成面霜的人相比,椰子油使用者的咬伤减少了15% (p = 0.01)。结论:这些发现强调了面霜的使用时间和净使用时间的保护作用,以及环境温度对咬伤结果的影响。特别是,椰子油在减少蚊虫叮咬方面的效果及其作为替代驱蚊剂的潜力已在实验室和现场环境中观察到。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Potential of coconut oil as a mosquito repellent.

Background: Naturally derived products have become popular as a mosquito repellent in addition to mosquito nets and chemical repellents. Coconut-derived fatty acids have demonstrated repellent properties against various blood-feeding arthropods, including mosquitoes. Daily use moisturizers and body soaps containing coconut have displayed some repellent effect against mosquitoes. However, no studies have been conducted on coconut oil specifically, and the effects of pure coconut oil still remain unknown in the western Kenya region.

Methods: In this study, we investigated the effect of coconut oil on decreasing mosquito bites in a laboratory and field setting. Using Anopheles stephensi mosquitoes, the laboratory experiment compared coconut oil treated and non-treated membranes on a Hemotek blood feeding device. In the cross-sectional study in western Kenya, we investigated bite counts among 490 children, 5 years and under. Descriptive analysis, simple, multiple and mixed regression models were employed. The outcome was the number of mosquito bite marks, the primary explanatory variable was skin cream types, in addition to demographic, environmental, behavioral and socio-economic variables.

Results: Coconut oil significantly reduced mosquito blood feeding, with a pooled Mantel-Haenszel odds ratio of 0.06, a Mantel-Haenszel chi-square statistic of 79.82 (p = 0.01), and an average blood-feeding rate of 1% compared to 31% in the control group. The mixed model identified significant factors influencing mosquito bite counts while accounting for village-level random effects. Coconut oil users experienced 15% reduction in bites (p = 0.01) compared to synthetic creams users. High and medium cream application frequencies reduced bites by 57% (p < 0.001) and 17% (p = 0.007), respectively. Late cream application and late net entry significantly increased bite counts by 41% (p < 0.001) and 53% (p < 0.001), respectively. In addition, higher temperatures from the preceding 2 weeks in the region was associated with a 26% (p = 0.003) increase in bite counts.

Conclusions: These findings underscore the protective impact of cream application and timing and net use timing, as well as environmental temperature influences on bite outcomes. Particularly, the effect of coconut oil in decreasing mosquito bites and its potential as an alternative repellent has been observed in both laboratory and field settings.

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来源期刊
Tropical Medicine and Health
Tropical Medicine and Health TROPICAL MEDICINE-
CiteScore
7.00
自引率
2.20%
发文量
90
审稿时长
11 weeks
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