{"title":"复发性多软骨炎伴甲状腺癌:马达加斯加首例病例。","authors":"Oliva Henintsoa Rakotonirainy, Mamonjisoa Olivier Andrianiaina, Lalao Nomenjanahary Rakotonirina, Volatantely Ratovonjanahary, Fahafahantsoa Rabenja Rapelanoro","doi":"10.1155/crot/1456640","DOIUrl":null,"url":null,"abstract":"<p><p>Relapsing polychondritis (RP) is a rare disease characterized by recurrent systemic inflammation affecting cartilaginous tissues and proteoglycan-rich tissues. The disease may present in several clinical variants, which can delay diagnosis. Corticosteroids are the treatment of choice for RP. In rare cases, RP can be paraneoplastic. The association of RP with thyroid cancer is unusual. We report the first Malagasy case of a 48-year-old man with RP type one diagnosed within less than a year, presenting with recurrent chondritis of the auricular cartilage, tracheobronchial chondritis, and recurrent episcleritis. The disease was associated with papillary thyroid carcinoma.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2025 ","pages":"1456640"},"PeriodicalIF":0.4000,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008485/pdf/","citationCount":"0","resultStr":"{\"title\":\"Relapsing Polychondritis Associated With Thyroid Carcinoma: A First Malagasy Case.\",\"authors\":\"Oliva Henintsoa Rakotonirainy, Mamonjisoa Olivier Andrianiaina, Lalao Nomenjanahary Rakotonirina, Volatantely Ratovonjanahary, Fahafahantsoa Rabenja Rapelanoro\",\"doi\":\"10.1155/crot/1456640\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Relapsing polychondritis (RP) is a rare disease characterized by recurrent systemic inflammation affecting cartilaginous tissues and proteoglycan-rich tissues. The disease may present in several clinical variants, which can delay diagnosis. Corticosteroids are the treatment of choice for RP. In rare cases, RP can be paraneoplastic. The association of RP with thyroid cancer is unusual. We report the first Malagasy case of a 48-year-old man with RP type one diagnosed within less than a year, presenting with recurrent chondritis of the auricular cartilage, tracheobronchial chondritis, and recurrent episcleritis. The disease was associated with papillary thyroid carcinoma.</p>\",\"PeriodicalId\":45872,\"journal\":{\"name\":\"Case Reports in Otolaryngology\",\"volume\":\"2025 \",\"pages\":\"1456640\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2025-04-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008485/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Otolaryngology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/crot/1456640\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"OTORHINOLARYNGOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Otolaryngology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/crot/1456640","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
Relapsing Polychondritis Associated With Thyroid Carcinoma: A First Malagasy Case.
Relapsing polychondritis (RP) is a rare disease characterized by recurrent systemic inflammation affecting cartilaginous tissues and proteoglycan-rich tissues. The disease may present in several clinical variants, which can delay diagnosis. Corticosteroids are the treatment of choice for RP. In rare cases, RP can be paraneoplastic. The association of RP with thyroid cancer is unusual. We report the first Malagasy case of a 48-year-old man with RP type one diagnosed within less than a year, presenting with recurrent chondritis of the auricular cartilage, tracheobronchial chondritis, and recurrent episcleritis. The disease was associated with papillary thyroid carcinoma.