{"title":"代谢组学在肾脏疾病生物标志物鉴定中的应用。","authors":"Swarnima Pandey","doi":"10.7150/ntno.108320","DOIUrl":null,"url":null,"abstract":"<p><p>With the apparent rise in lifestyle-related changes, there has been a significant decline in renal health. Metabolomics plays a crucial role in the prognosis, diagnosis, and treatment of various renal conditions, including chronic kidney disease, acute kidney injury, diabetic kidney disease, kidney cancer, and post-transplant complications. Metabolomics has identified novel biomarkers, providing insights into altered pathways and potential therapeutic targets for kidney diseases. Kidney diseases and metabolomics keywords were searched in correspondence with the assigned keywords, including chronic kidney diseases, acute kidney injury, kidney carcinoma, kidney transplant, and diabetic kidney diseases on literature search engines. The applicable studies from this search were extracted and included in the study. This review is focused on the biomarkers identified in different kidney diseases such as chronic kidney diseases, acute kidney injury, diabetic kidney disease, kidney carcinoma and kidney transplant.</p>","PeriodicalId":36934,"journal":{"name":"Nanotheranostics","volume":"9 2","pages":"110-120"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980039/pdf/","citationCount":"0","resultStr":"{\"title\":\"Metabolomics for the Identification of Biomarkers in Kidney Diseases.\",\"authors\":\"Swarnima Pandey\",\"doi\":\"10.7150/ntno.108320\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>With the apparent rise in lifestyle-related changes, there has been a significant decline in renal health. Metabolomics plays a crucial role in the prognosis, diagnosis, and treatment of various renal conditions, including chronic kidney disease, acute kidney injury, diabetic kidney disease, kidney cancer, and post-transplant complications. Metabolomics has identified novel biomarkers, providing insights into altered pathways and potential therapeutic targets for kidney diseases. Kidney diseases and metabolomics keywords were searched in correspondence with the assigned keywords, including chronic kidney diseases, acute kidney injury, kidney carcinoma, kidney transplant, and diabetic kidney diseases on literature search engines. The applicable studies from this search were extracted and included in the study. This review is focused on the biomarkers identified in different kidney diseases such as chronic kidney diseases, acute kidney injury, diabetic kidney disease, kidney carcinoma and kidney transplant.</p>\",\"PeriodicalId\":36934,\"journal\":{\"name\":\"Nanotheranostics\",\"volume\":\"9 2\",\"pages\":\"110-120\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-03-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980039/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nanotheranostics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7150/ntno.108320\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q1\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nanotheranostics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7150/ntno.108320","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
Metabolomics for the Identification of Biomarkers in Kidney Diseases.
With the apparent rise in lifestyle-related changes, there has been a significant decline in renal health. Metabolomics plays a crucial role in the prognosis, diagnosis, and treatment of various renal conditions, including chronic kidney disease, acute kidney injury, diabetic kidney disease, kidney cancer, and post-transplant complications. Metabolomics has identified novel biomarkers, providing insights into altered pathways and potential therapeutic targets for kidney diseases. Kidney diseases and metabolomics keywords were searched in correspondence with the assigned keywords, including chronic kidney diseases, acute kidney injury, kidney carcinoma, kidney transplant, and diabetic kidney diseases on literature search engines. The applicable studies from this search were extracted and included in the study. This review is focused on the biomarkers identified in different kidney diseases such as chronic kidney diseases, acute kidney injury, diabetic kidney disease, kidney carcinoma and kidney transplant.