Edwin O Ogola, Amitava Roy, Kurt Wollenberg, Missiani Ochwoto, Marshall E Bloom
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Strange relatives: the enigmatic arbo-jingmenviruses and orthoflaviviruses.
Arthropod - and vertebrate-associated jingmenviruses (arbo-JMV) have segmented positive-strand RNA genomes and are provisional members of the genus Orthoflavivirus (family Flaviviridae). Current investigations have described arbo-JMV infection in vertebrate hosts in proximity to humans. This raises concerns about the virus host range and public health implications. This review explores the genomic and evolutionary relationship between arbo-JMV and orthoflaviviruses and evaluates the potential of arbo-JMV to pose a public health threat.
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