Carla Gabriela Guzmán-Mendoza, María Del Carmen Jiménez-González, Oscar Manuel Delgado-Cuellar, Iván de Jesús Ascencio-Montiel
{"title":"[抗逆转录病毒治疗依从性及其与抑郁、焦虑和压力的关系]。","authors":"Carla Gabriela Guzmán-Mendoza, María Del Carmen Jiménez-González, Oscar Manuel Delgado-Cuellar, Iván de Jesús Ascencio-Montiel","doi":"10.5281/zenodo.14616894","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Stress, anxiety, and depression are associated with low adherence to antiretroviral therapy (ART) in HIV patients, but there are no reports of this association in southeastern Mexico.</p><p><strong>Objective: </strong>To describe the frequency of adherence to ART and its association with depression, anxiety, and stress.</p><p><strong>Material and methods: </strong>A cross-sectional study was conducted. 442 HIV-positive outpatients treated at General Hospital Number 1 in Tapachula, Chiapas, in the period August-December 2022 were analyzed. Adherence to ART was assessed with the Simplified Medication Adherence Questionnaire (SMAQ) and the Depression, Anxiety, and Stress Scale-21 (DASS-21) was applied. To assess the association between variables, adjusted odds ratios (aOR) with 95% confidence intervals (CI) were calculated using a multivariate logistic regression model. Cases with ART adherence between 95% and 100% were compared with those with ART adherence below 95%.</p><p><strong>Results: </strong>Of the total 442 HIV-positive subjects, 344 had ART adherence between 95% and 100%, and 98 had ART adherence below 95%. The frequencies of depression, anxiety, and stress were 33%, 13.3%, and 8.8%, respectively. Associations were observed between ART adherence below 95% and anxiety, depression, and stress.</p><p><strong>Conclusions: </strong>Since low ART adherence was associated with depression, anxiety, and stress among HIV-positive patients, early mental health interventions may help improve therapeutic adherence.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 2","pages":"e6553"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040392/pdf/","citationCount":"0","resultStr":"{\"title\":\"[ART adherence and its association with depression, anxiety and stress].\",\"authors\":\"Carla Gabriela Guzmán-Mendoza, María Del Carmen Jiménez-González, Oscar Manuel Delgado-Cuellar, Iván de Jesús Ascencio-Montiel\",\"doi\":\"10.5281/zenodo.14616894\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Stress, anxiety, and depression are associated with low adherence to antiretroviral therapy (ART) in HIV patients, but there are no reports of this association in southeastern Mexico.</p><p><strong>Objective: </strong>To describe the frequency of adherence to ART and its association with depression, anxiety, and stress.</p><p><strong>Material and methods: </strong>A cross-sectional study was conducted. 442 HIV-positive outpatients treated at General Hospital Number 1 in Tapachula, Chiapas, in the period August-December 2022 were analyzed. Adherence to ART was assessed with the Simplified Medication Adherence Questionnaire (SMAQ) and the Depression, Anxiety, and Stress Scale-21 (DASS-21) was applied. To assess the association between variables, adjusted odds ratios (aOR) with 95% confidence intervals (CI) were calculated using a multivariate logistic regression model. Cases with ART adherence between 95% and 100% were compared with those with ART adherence below 95%.</p><p><strong>Results: </strong>Of the total 442 HIV-positive subjects, 344 had ART adherence between 95% and 100%, and 98 had ART adherence below 95%. The frequencies of depression, anxiety, and stress were 33%, 13.3%, and 8.8%, respectively. Associations were observed between ART adherence below 95% and anxiety, depression, and stress.</p><p><strong>Conclusions: </strong>Since low ART adherence was associated with depression, anxiety, and stress among HIV-positive patients, early mental health interventions may help improve therapeutic adherence.</p>\",\"PeriodicalId\":94200,\"journal\":{\"name\":\"Revista medica del Instituto Mexicano del Seguro Social\",\"volume\":\"63 2\",\"pages\":\"e6553\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-03-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040392/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista medica del Instituto Mexicano del Seguro Social\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5281/zenodo.14616894\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista medica del Instituto Mexicano del Seguro Social","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5281/zenodo.14616894","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[ART adherence and its association with depression, anxiety and stress].
Background: Stress, anxiety, and depression are associated with low adherence to antiretroviral therapy (ART) in HIV patients, but there are no reports of this association in southeastern Mexico.
Objective: To describe the frequency of adherence to ART and its association with depression, anxiety, and stress.
Material and methods: A cross-sectional study was conducted. 442 HIV-positive outpatients treated at General Hospital Number 1 in Tapachula, Chiapas, in the period August-December 2022 were analyzed. Adherence to ART was assessed with the Simplified Medication Adherence Questionnaire (SMAQ) and the Depression, Anxiety, and Stress Scale-21 (DASS-21) was applied. To assess the association between variables, adjusted odds ratios (aOR) with 95% confidence intervals (CI) were calculated using a multivariate logistic regression model. Cases with ART adherence between 95% and 100% were compared with those with ART adherence below 95%.
Results: Of the total 442 HIV-positive subjects, 344 had ART adherence between 95% and 100%, and 98 had ART adherence below 95%. The frequencies of depression, anxiety, and stress were 33%, 13.3%, and 8.8%, respectively. Associations were observed between ART adherence below 95% and anxiety, depression, and stress.
Conclusions: Since low ART adherence was associated with depression, anxiety, and stress among HIV-positive patients, early mental health interventions may help improve therapeutic adherence.
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