小儿肺炎的局部与全身细胞因子动力学。

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Pulmonology Pub Date : 2025-04-01 DOI:10.1002/ppul.71093

Jilei Lin, Mingyu Tang, Shuhua Yuan, Jiande Chen, Guijun Yang, Huishan Zhang, Wanlin Li, Jing Zhang, Lei Zhang, Yong Yin

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引用次数: 0

摘要

大多数局部和全身细胞因子在肺炎患儿中没有明显的相关性。观察到肺炎患者BALF中IL-2、IL-2R和IL-4等特异性细胞因子的升高，以及外周血中IL-2、IL-6和IL-12p70的升高，强调了肺炎中强大的局部和全身炎症反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Local Versus Systemic Cytokine Dynamics in Pediatric Pneumonia.

No significant correlation was observed between most local and systemic cytokines in children with pneumonia. The observed elevation of specific cytokines such as IL-2, IL-2R, and IL-4 in the BALF of pneumonia patients, alongside increases in IL-2, IL-6, and IL-12p70 in peripheral blood, underscores the robust local and systemic inflammatory response in pneumonia.

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来源期刊

Pediatric Pulmonology 医学-呼吸系统

CiteScore

6.00

自引率

12.90%

发文量

468

审稿时长

3-8 weeks

期刊介绍： Pediatric Pulmonology (PPUL) is the foremost global journal studying the respiratory system in disease and in health as it develops from intrauterine life though adolescence to adulthood. Combining explicit and informative analysis of clinical as well as basic scientific research, PPUL provides a look at the many facets of respiratory system disorders in infants and children, ranging from pathological anatomy, developmental issues, and pathophysiology to infectious disease, asthma, cystic fibrosis, and airborne toxins. Focused attention is given to the reporting of diagnostic and therapeutic methods for neonates, preschool children, and adolescents, the enduring effects of childhood respiratory diseases, and newly described infectious diseases. PPUL concentrates on subject matters of crucial interest to specialists preparing for the Pediatric Subspecialty Examinations in the United States and other countries. With its attentive coverage and extensive clinical data, this journal is a principle source for pediatricians in practice and in training and a must have for all pediatric pulmonologists.