登山白垩止血性能的比较分析。

IF 1.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Wilderness & Environmental Medicine Pub Date : 2025-09-01 Epub Date: 2025-04-10 DOI:10.1177/10806032251326025
Mark Raymond, Brooke Solberg
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引用次数: 0

摘要

攀岩粉笔被攀岩者和运动员广泛使用,以提高抓地力。据观察,登山者有时会将碳酸镁白垩涂在小伤口上止血,这表明登山白垩可能对小伤口和擦伤有止血作用。本研究旨在探讨和比较不同类型攀岩白垩对凝血酶原时间(PT)和活化部分凝血活素时间(aPTT)的影响。方法随机选择3种登山白垩进行止血性能对比分析,并以滑石粉为阴性对照。对含有不同浓度攀爬白垩(0.125 mg/mL ~ 4mg /mL)的正常血浆样品进行PT和aPTT检测。采用双尾t检验、Welch方差分析(ANOVA)和Games-Howell事后分析对结果进行统计分析。结果与阴性对照相比,攀白垩粉对PT无显著影响,但显著降低aPTT。进一步的分析显示,不同类型的白垩以及高浓度和低浓度的白垩在aPTT结果上存在显著差异。结论碳酸镁攀岩粉具有促凝止血作用,可能通过影响凝血级联的内在途径实现。虽然需要进一步研究以更好地了解其凝固特性,但攀岩白垩在荒野医学中显示出作为轻微伤口止血剂的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hemostatic Properties of Climbing Chalk: A Comparative Analysis.

IntroductionClimbing chalk is widely used by rock climbers and athletes to improve grip. It has been observed that climbers sometimes apply magnesium carbonate chalk to small wounds to stop bleeding, suggesting that climbing chalk may exhibit hemostatic properties useful for small cuts and scrapes. This study aimed to investigate and compare the effects of different types of climbing chalk on prothrombin time (PT) and activated partial thromboplastin time (aPTT).MethodsThree types of climbing chalk were randomly selected for comparative analysis of hemostatic properties, with talcum powder used as a negative control. PT and aPTT testing were conducted on normal plasma samples containing varying concentrations of climbing chalk (from 0.125 mg/mL to 4 mg/mL). Statistical analyses of the results were performed using two-tailed t-tests, Welch's analysis of variance (ANOVA), and Games-Howell post-hoc analysis.ResultsResults indicated that climbing chalk had no significant effect on PT but did significantly reduce aPTT compared to the negative control. Additional analyses revealed significant differences in aPTT results between different types of chalk and between higher and lower concentrations of chalk.ConclusionsMagnesium carbonate-based climbing chalks appear to have a procoagulant effect on hemostasis, likely by affecting the intrinsic pathway of the coagulation cascade. While further research is needed to better understand its coagulative properties, climbing chalk shows potential as a hemostatic agent for minor wounds in wilderness medicine.

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来源期刊
Wilderness & Environmental Medicine
Wilderness & Environmental Medicine 医学-公共卫生、环境卫生与职业卫生
CiteScore
2.10
自引率
7.10%
发文量
96
审稿时长
>12 weeks
期刊介绍: Wilderness & Environmental Medicine, the official journal of the Wilderness Medical Society, is the leading journal for physicians practicing medicine in austere environments. This quarterly journal features articles on all aspects of wilderness medicine, including high altitude and climbing, cold- and heat-related phenomena, natural environmental disasters, immersion and near-drowning, diving, and barotrauma, hazardous plants/animals/insects/marine animals, animal attacks, search and rescue, ethical and legal issues, aeromedial transport, survival physiology, medicine in remote environments, travel medicine, operational medicine, and wilderness trauma management. It presents original research and clinical reports from scientists and practitioners around the globe. WEM invites submissions from authors who want to take advantage of our established publication''s unique scope, wide readership, and international recognition in the field of wilderness medicine. Its readership is a diverse group of medical and outdoor professionals who choose WEM as their primary wilderness medical resource.
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