Kezhong Chen, Anwen Liu, Changli Wang, Chengping Hu, Chun Chen, Fan Yang, Haiquan Chen, Hongbing Shen, Hongtao Zhang, Hongxu Liu, Jianping Xiong, Jie Wang, Li Zhang, Lin Xu, Lvhua Wang, Mingfang Zhao, Qiang Li, Qibin Song, Qinghua Zhou, Qun Wang, Shenglin Ma, Shidong Xu, Shuanghu Yuan, Shugeng Gao, Shun Lu, Weimin Li, Weimin Mao, Xiaoqing Liu, Xiaorong Dong, Xuening Yang, Yilong Wu, Ying Cheng, Yong Song, Yunchao Huang, Zhenfa Zhang, Zhiwei Chen, Zhiyong Ma, Christoph C Zielinski, Yu Shyr, Jun Wang
{"title":"多学科专家对多发性肺癌诊断和治疗的共识。","authors":"Kezhong Chen, Anwen Liu, Changli Wang, Chengping Hu, Chun Chen, Fan Yang, Haiquan Chen, Hongbing Shen, Hongtao Zhang, Hongxu Liu, Jianping Xiong, Jie Wang, Li Zhang, Lin Xu, Lvhua Wang, Mingfang Zhao, Qiang Li, Qibin Song, Qinghua Zhou, Qun Wang, Shenglin Ma, Shidong Xu, Shuanghu Yuan, Shugeng Gao, Shun Lu, Weimin Li, Weimin Mao, Xiaoqing Liu, Xiaorong Dong, Xuening Yang, Yilong Wu, Ying Cheng, Yong Song, Yunchao Huang, Zhenfa Zhang, Zhiwei Chen, Zhiyong Ma, Christoph C Zielinski, Yu Shyr, Jun Wang","doi":"10.1016/j.medj.2025.100643","DOIUrl":null,"url":null,"abstract":"<p><p>The rising incidence of multiple lung cancers (MLCs), encompassing multiple primary lung cancers (MPLCs) and intrapulmonary metastasis (IPM), poses two significant clinical challenges. First, distinguishing between MPLC and IPM remains difficult due to insufficiently accurate criteria and ambiguous integration of genetic testing. Second, standardized therapeutic protocols are still lacking. To address these issues, the Lung Cancer Expert Committee of China Anti-Cancer Association (CACA) assembled a multidisciplinary expert panel spanning thoracic surgery, pulmonary medicine, oncology, radiology, and pathology. Following a comprehensive literature review ending on October 23, 2024, the panel engaged in iterative discussions and conducted two rounds of expert voting, culminating in 25 evidence-based recommendations across five key domains: epidemiology, pre-treatment evaluation, definitive diagnostics, surgical treatment, and non-surgical treatment. This consensus provides clinicians with practical guidance to enhance diagnostic precision and therapeutic decision-making in MLC management while highlighting unmet needs to inform future guideline development.</p>","PeriodicalId":29964,"journal":{"name":"Med","volume":"6 4","pages":"100643"},"PeriodicalIF":12.8000,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Multidisciplinary expert consensus on diagnosis and treatment of multiple lung cancers.\",\"authors\":\"Kezhong Chen, Anwen Liu, Changli Wang, Chengping Hu, Chun Chen, Fan Yang, Haiquan Chen, Hongbing Shen, Hongtao Zhang, Hongxu Liu, Jianping Xiong, Jie Wang, Li Zhang, Lin Xu, Lvhua Wang, Mingfang Zhao, Qiang Li, Qibin Song, Qinghua Zhou, Qun Wang, Shenglin Ma, Shidong Xu, Shuanghu Yuan, Shugeng Gao, Shun Lu, Weimin Li, Weimin Mao, Xiaoqing Liu, Xiaorong Dong, Xuening Yang, Yilong Wu, Ying Cheng, Yong Song, Yunchao Huang, Zhenfa Zhang, Zhiwei Chen, Zhiyong Ma, Christoph C Zielinski, Yu Shyr, Jun Wang\",\"doi\":\"10.1016/j.medj.2025.100643\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The rising incidence of multiple lung cancers (MLCs), encompassing multiple primary lung cancers (MPLCs) and intrapulmonary metastasis (IPM), poses two significant clinical challenges. First, distinguishing between MPLC and IPM remains difficult due to insufficiently accurate criteria and ambiguous integration of genetic testing. Second, standardized therapeutic protocols are still lacking. To address these issues, the Lung Cancer Expert Committee of China Anti-Cancer Association (CACA) assembled a multidisciplinary expert panel spanning thoracic surgery, pulmonary medicine, oncology, radiology, and pathology. Following a comprehensive literature review ending on October 23, 2024, the panel engaged in iterative discussions and conducted two rounds of expert voting, culminating in 25 evidence-based recommendations across five key domains: epidemiology, pre-treatment evaluation, definitive diagnostics, surgical treatment, and non-surgical treatment. This consensus provides clinicians with practical guidance to enhance diagnostic precision and therapeutic decision-making in MLC management while highlighting unmet needs to inform future guideline development.</p>\",\"PeriodicalId\":29964,\"journal\":{\"name\":\"Med\",\"volume\":\"6 4\",\"pages\":\"100643\"},\"PeriodicalIF\":12.8000,\"publicationDate\":\"2025-04-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Med\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.medj.2025.100643\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Med","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.medj.2025.100643","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Multidisciplinary expert consensus on diagnosis and treatment of multiple lung cancers.
The rising incidence of multiple lung cancers (MLCs), encompassing multiple primary lung cancers (MPLCs) and intrapulmonary metastasis (IPM), poses two significant clinical challenges. First, distinguishing between MPLC and IPM remains difficult due to insufficiently accurate criteria and ambiguous integration of genetic testing. Second, standardized therapeutic protocols are still lacking. To address these issues, the Lung Cancer Expert Committee of China Anti-Cancer Association (CACA) assembled a multidisciplinary expert panel spanning thoracic surgery, pulmonary medicine, oncology, radiology, and pathology. Following a comprehensive literature review ending on October 23, 2024, the panel engaged in iterative discussions and conducted two rounds of expert voting, culminating in 25 evidence-based recommendations across five key domains: epidemiology, pre-treatment evaluation, definitive diagnostics, surgical treatment, and non-surgical treatment. This consensus provides clinicians with practical guidance to enhance diagnostic precision and therapeutic decision-making in MLC management while highlighting unmet needs to inform future guideline development.
期刊介绍：
Med is a flagship medical journal published monthly by Cell Press, the global publisher of trusted and authoritative science journals including Cell, Cancer Cell, and Cell Reports Medicine. Our mission is to advance clinical research and practice by providing a communication forum for the publication of clinical trial results, innovative observations from longitudinal cohorts, and pioneering discoveries about disease mechanisms. The journal also encourages thought-leadership discussions among biomedical researchers, physicians, and other health scientists and stakeholders. Our goal is to improve health worldwide sustainably and ethically.
Med publishes rigorously vetted original research and cutting-edge review and perspective articles on critical health issues globally and regionally. Our research section covers clinical case reports, first-in-human studies, large-scale clinical trials, population-based studies, as well as translational research work with the potential to change the course of medical research and improve clinical practice.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
