经导管主动脉瓣置换术中冠状动脉阻塞的风险及保护策略。

Q2 Medicine
Yanren Peng, Ruqiong Nie, Haifeng Zhang
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引用次数: 0

摘要

经导管主动脉瓣置换术(TAVR)已成为主动脉瓣狭窄的一线治疗方法。冠状动脉阻塞是TAVR的严重并发症,死亡率超过30%。冠状动脉梗阻根据发病时间可分为急性梗阻和迟发性梗阻,根据发病机制可分为直接梗阻和间接梗阻。预测冠状动脉梗阻的危险因素包括:Valsalva直径小、原生小叶过长、冠状动脉高度低、肾小管交界处高度和直径小。术前使用CT准确评估这些解剖参数对于选择合适的瓣膜类型、大小和植入深度至关重要。冠状动脉阻塞的预防技术策略包括术中介入治疗(如“烟囱”支架置入技术)、小叶修饰(如BASILICA技术)以及环和冠状动脉对齐。这些技术在降低冠状动脉阻塞发生率和相关死亡率方面已经证明了显著的疗效。本文综述了冠状动脉梗阻的流行病学、分类和发病机制,重点介绍了高危患者的识别、预防和治疗。目的是强调在TAVR中认识和管理冠状动脉风险的重要性,并为临床实践中预防和治疗冠状动脉阻塞提供可操作的建议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Risk of coronary obstruction and protection strategies in transcatheter aortic valve replacement].

Transcatheter aortic valve replacement (TAVR) has emerged as the first-line treatment for aortic valve stenosis. Coronary obstruction is a severe complication of TAVR, with mortality rates exceeding 30%. Coronary obstruction can be classified as acute or delayed based on the timing of the onset, and as direct or indirect obstruction according to the underlying mechanism. Risk factors for predicting coronary obstruction include a small sinus of Valsalva diameter, excessively long native leaflets, low coronary height, and small sinotubular junction height and diameter. Accurate preoperative assessment of these anatomical parameters using CT is crucial for selecting the appropriate valve type, size, and implantation depth. Preventive technical strategies for coronary obstruction include intraoperative interventional treatments (such as the "Chimney" stenting technique), leaflet modification (such as the BASILICA technique), and alignment of the annulus and coronaries. These techniques have demonstrated significant efficacy in reducing the incidence of coronary obstruction and associated mortality. This paper reviews the epidemiology, classification, and mechanisms of coronary obstruction, with a particular focus on the identification, prevention, and treatment of high-risk patients. The aim is to highlight the importance of recognizing and managing coronary risks during TAVR and to provide actionable recommendations for the prevention and treatment of coronary obstruction in clinical practice.

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CiteScore
3.80
自引率
0.00%
发文量
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