慢性肠大气瘘引起的鳞状细胞癌。

IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Phillip Alix, Genesis Moseley, Shai Chazin, Courtland Polley, Steven Bowers, Amanda P Stanton
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引用次数: 0

摘要

摘要:马卓林溃疡是一种侵袭性皮肤恶性肿瘤,通常由慢性、不愈合的伤口引起。明显缺陷的存在往往掩盖了这种可能危及生命的疾病,使检测变得困难,并经常导致诊断延误。在组织学上,大多数马氏溃疡为鳞状细胞癌。与其他常见的皮肤恶性肿瘤不同,对于马卓林溃疡的早期监测和管理尚无明确的指导方针或方案。考虑到这种恶性肿瘤的侵袭性,当伴有转移时,早期诊断和干预是必要的。我们报告了一个独特的病例,描述了一个免疫功能低下的病人,他有广泛的外科腹部病史,在最终组织学上发现了一个皮肤肿块,被确定为分化良好的侵袭性鳞状细胞癌。肿块叠加在慢性肠大气瘘,存在超过20年。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Squamous cell carcinoma arising from chronic enteroatmospheric fistula.

Abstract: Marjolin ulcers are aggressive, cutaneous malignancies typically arising from chronic, nonhealing wounds. The presence of an obvious defect often masks this potentially life-threatening condition, making detection difficult and frequently leading to delayed diagnosis. Most cases of Marjolin ulcers are squamous cell carcinoma (SCC) in histology. Unlike for other common cutaneous malignancies, no clear guidelines or protocols are in place for early surveillance and management of Marjolin ulcers. Given the aggressive nature of this malignancy when associated with metastasis, early diagnosis and intervention are imperative. We present a unique case describing an immunocompromised patient with an extensive surgical abdominal history who had developed a cutaneous mass determined to be well-differentiated invasive SCC on final histology. The mass was superimposed over a chronic enteroatmospheric fistula that was present for more than 20 years.

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来源期刊
CiteScore
1.20
自引率
9.10%
发文量
310
期刊介绍: ​​​JAAPA is the peer-reviewed clinical journal of the American Academy of Physician Assistants (AAPA). Published for more than 25 years, its mission is to support the ongoing education and advancement of physician assistants (PAs) by publishing current information and research on clinical, health policy, and professional issues. Published monthly, JAAPA''s award-winning editorial includes: -Clinical review articles (with AAPA-approved Category I CME in each issue)- Case reports- Clinical departments- Original health services research- Articles on issues of professional interest to PAs
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