纳米羟基磷灰石是骨再生的关键因素。

Q4 Medicine
Paweł Kamiński, Mateusz Kaczmarski, Marta Żerebiec, Natalia Saj, Aleksandra Bełżek, Zuzanna Rupeć, Karolina Turżańska, Małgorzata Drelich
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引用次数: 0

摘要

骨组织是一种复杂的材料,具有显著的耐久性、弹性和抗机械力,在肌肉骨骼系统中起着关键作用。羟基磷灰石是一种天然存在的类骨矿物,由于其与骨组织的相容性,被用于各种医学应用。然而,人工合成的羟基磷灰石存在一些局限性,如易碎性和抗机械应变能力差。纳米技术的最新发展导致了纳米羟基磷灰石的发明,它可以促进骨再生和与周围组织的整合。该研究的目的是引起人们对纳米羟基磷灰石在临床实践中日益增长的潜力的关注,特别是在骨缺损的治疗中。利用PubMed和谷歌Scholar网站,根据具体标准进行综合文献综述,找出纳米羟基磷灰石临床应用的相关研究,并评价其与其他有机和无机材料的有效性和适用性。纳米羟基磷灰石已经在体外、体内和临床试验中进行了广泛的研究,显示出增强骨再生和整合的能力。动物模型研究显示纳米羟基磷灰石在骨愈合和预防感染方面有良好的效果。临床研究也证实了其在骨移植中的有效性,显示出与自体骨移植相当的结果,并且比其他合成材料的并发症更少。纳米羟基磷灰石是一种很有前途的现代医学生物材料。在临床应用中证明了与天然骨组织相当的有效性,在骨再生、种植体整合和组织愈合方面显示出巨大的希望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nanohydroxyapatite as the key factor in bone regeneration.

Bone tissue is a complex material with remarkable durability, elasticity and resistance to mechanical forces, playing a key role in the musculoskeletal system. Hydroxyapatite, a naturally occurring bone-like mineral, is used in a variety of medical applications due to its compatibility with bone tissue. However, synthetic hydroxyapatite has some limitations, such as fragility and low resistance to mechanical straining. Recent developments in nanotechnology have led to the invention of nanohydroxyapatite, which improves bone regeneration and integration with surrounding tissues. The aim of the study is to draw attention to the growing potential of nanohydroxyapatite in clinical practice, especially in the treatment of bone defects. A comprehensive literature review was conducted using PubMed and Google Scholar based on specific criteria to identify relevant studies on the clinical application of nanohydroxyapatite and evaluate its effectiveness and applicability with other organic and inorganic materials. Nanohydroxyapatite has been extensively studied in vitro, in vivo and in clinical trials, showing enhanced bone regeneration and integration. Studies in animal models show promising results for nanohydroxyapatite in bone healing and infection prevention. Clinical studies also confirm its effectiveness in bone grafts, showing comparable results to autografts and fewer complications than other synthetic materials. Nanohydroxyapatite represents a promising biomaterial in modern medicine. Demonstrating effectiveness comparable to natural bone tissue in clinical applications, it exhibits great promise in bone regeneration, implant integration and tissue healing.

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来源期刊
Wiadomosci lekarskie
Wiadomosci lekarskie Medicine-Medicine (all)
CiteScore
0.80
自引率
0.00%
发文量
482
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