用于儿童先天性白内障患者的可调臂型扫描源光学相干断层扫描系统的研制。

IF 2.3
Wuge Shama, Sisi Chen, Wanyu Su, Yinglong Lan, Shilei Wang, Peifeng Zhang, Yue Jin, Zhangliang Li, Yun-E Zhao, Fan Lu, Meixiao Shen
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引用次数: 0

摘要

我们开发了一种稳定的、高穿透性的臂型扫描源光学相干断层扫描(SS-OCT)系统,用于观察先天性白内障儿童患者的视网膜和脉络膜结构。该系统的特点是一个紧凑的OCT探头,集成了虹膜相机和固定目标,便于校准,安装在一个五自由度可调节的手臂上,以减少运动伪影和操作员疲劳。通过对健康成人、先天性白内障儿童和婴儿的仰卧视网膜成像证明了该方法的可行性,成功率分别为100%、97%和95%。该系统捕捉先天性白内障患者视网膜异常特征(如中央凹结构缺失),突出了其监测视网膜发育的临床价值。高速(200 kHz)成像和高分辨率(4.1 μm)进一步支持其在临床诊断和科学研究中的双重作用,如视网膜发育研究和视觉预后建模。该系统在临床实践和研究中具有重要的常规应用潜力,为儿童眼科成像提供了可靠的工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Development of an Adjustable Arm-Type Swept-Source Optical Coherence Tomography System for Pediatric Patients With Congenital Cataracts.

We developed a stable, high-penetration arm-type swept-source optical coherence tomography (SS-OCT) system for visualizing retinal and choroidal structures in pediatric patients with congenital cataracts. The system features a compact OCT probe with an integrated iris camera and fixation target for easy alignment, mounted on a five-degree-of-freedom adjustable arm to reduce motion artifacts and operator fatigue. Feasibility was demonstrated through supine retinal imaging of healthy adults, congenital cataract children, and infants, achieving success rates of 100%, 97%, and 95%, respectively. The system captured abnormal retinal features (e.g., absent foveal structure) in congenital cataract patients, highlighting its clinical value for monitoring retinal development. High-speed (200 kHz) imaging and high-resolution (4.1 μm) further support its dual role in clinical diagnosis and scientific research, such as retinal development studies and visual prognosis modeling. This system demonstrates significant potential for routine use in clinical practice and research, offering a reliable tool for pediatric ophthalmic imaging.

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