成人冠状动脉搭桥术及瓣膜手术围手术期的处理:文献综述。

IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL
Einstein-Sao Paulo Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI:10.31744/einstein_journal/2025RW1353
Nair Naiara Barros de Vasconcelos, Veronica Neves Fialho Queiroz, Guilherme Martins de Souza, Sandrigo Mangini, Fernando Morita Fernandes Silva, Luiz Guilherme Villares da Costa, Pedro Paulo Zanella do Amaral Campos, Samuel Padovani Steffen, Flávio Takaoka, Ary Serpa Neto, Adriano José Pereira, Carmen Silvia Valente Barbas, Thiago Domingos Corrêa, Renato Carneiro de Freitas Chaves
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引用次数: 0

摘要

综述目的:冠状动脉旁路移植术、经皮冠状动脉介入血管重建术和心脏瓣膜手术是治疗各种心血管疾病的重要手段。本文献综述的目的是介绍冠状动脉旁路移植术和心脏瓣膜手术患者围手术期管理的主要证据和实践方面。最新发现:尽管手术和麻醉技术取得了进步,冠状动脉旁路移植术和心脏瓣膜手术仍存在明显的围手术期并发症和死亡风险。这些并发症增加了发病率、死亡率和住院时间。冠状动脉旁路移植术适用于有明显左主干病变或晚期冠状动脉病变的患者。大多数接受冠状动脉旁路移植术且预期寿命合理的患者被建议采用多动脉移植策略,使用两到三条动脉移植。经皮冠状动脉介入血管重建术经常用于缓解稳定性心绞痛和冠状动脉狭窄引起中度或重度缺血的患者的症状。术中凝血管理应包括麻醉诱导后的氨甲环酸和体外循环终止后立即的鱼精蛋白。不建议预防性使用新鲜冷冻血浆、去氨加压素、重组活化因子7或纤维蛋白原来减少出血。吸入麻醉剂具有公认的心脏保护特性;然而,挥发性麻醉剂是否能降低择期手术患者的死亡率尚不清楚。超声心动图在患者围术期管理中具有明确心肌结构、评估心内血流、辅助术前评估、方便术中监测、实时指导干预等重要作用。冠状动脉旁路移植术、经皮冠状动脉介入治疗和心脏瓣膜手术患者的围手术期管理非常复杂,涉及许多特定情况。有效的管理需要专门的多学科团队,能够及时识别、预防和治疗,以确保适当的护理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Perioperative management of adult patients undergoing coronary artery bypass grafting and valve surgery: a literature review.

Purpose of review: Coronary artery bypass grafting, revascularization by percutaneous coronary intervention, and heart valve surgery are crucial therapeutic interventions for patients with various cardiovascular diseases. The objective of this literature review was to present the main evidence and practical aspects of the perioperative management of patients undergoing coronary artery bypass grafting and heart valve surgery.

Recent findings: Despite advancements in surgical and anesthetic techniques, coronary artery bypass grafting and heart valve surgery present significant risks for perioperative complications and death. These complications increase morbidity, mortality, and length of hospital stay. Coronary artery bypass grafting is indicated for patients with significant left main or advanced coronary artery disease. Most patients undergoing coronary artery bypass grafting with a reasonable life expectancy are advised to adopt a multiple-arterial graft strategy using two or three arterial grafts. Revascularization by percutaneous coronary intervention is frequently performed to alleviate symptoms in patients with stable angina and coronary artery stenoses causing moderate or severe ischemia. Intraoperative coagulation management should include tranexamic acid after the induction of anesthesia and protamine immediately after the termination of extracorporeal circulation. The prophylactic use of fresh-frozen plasma, desmopressin, recombinant activated factor VII, or fibrinogen to reduce bleeding is not recommended. Inhaled anesthetics have recognized cardioprotective properties; however, it is unclear whether anesthesia with a volatile agent can reduce mortality in patients undergoing elective surgery. Echocardiography plays an important role in the perioperative management of patients by defining myocardial structure, assessing intracardiac blood flow, aiding preoperative evaluation, facilitating intraoperative monitoring, and providing real-time guidance for intervention. The perioperative management of patients undergoing coronary artery bypass grafting, percutaneous coronary intervention, and heart valve surgery is highly complex and involves numerous specific conditions. Effective management requires dedicated multidisciplinary teams skilled in timely recognition, prevention, and treatment to ensure appropriate care.

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来源期刊
Einstein-Sao Paulo
Einstein-Sao Paulo MEDICINE, GENERAL & INTERNAL-
CiteScore
2.00
自引率
0.00%
发文量
210
审稿时长
38 weeks
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