短期补充100%越橘产品及其对超重/肥胖妇女身体成分和脂质特征的影响。

IF 3.4 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Metabolites Pub Date : 2025-03-24 DOI:10.3390/metabo15040218
Marta Habanova, Maros Bihari, Radek Latal, Martina Gažarova, Petra Lenártová, Jana Pastrnakova, Jadwiga Hamulka
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引用次数: 0

摘要

简介:超重和肥胖是主要的公共卫生问题,往往导致心血管风险增加。方法:这项为期八周的干预性研究考察了定期食用两种天然越橘产品是否能改善超重/肥胖女性的身体成分和脂质谱。共有30名参与者(年龄在50-60岁之间)被分配每天饮用125毫升100%越橘汁或10克100%越橘纤维,同时保持他们的习惯饮食和生活方式。结果:尽管两组患者的人体测量参数或血压没有明显变化,但两种干预措施都降低了低密度脂蛋白胆固醇(LDL-C),增加了高密度脂蛋白胆固醇(HDL-C)。令人惊讶的是,越橘汁组的总胆固醇(TC)水平上升(从6.41±1.23 mmol/L到6.94±1.30 mmol/L (p < 0.001)),纤维组的总胆固醇(TC)水平上升(从6.06±1.39 mmol/L到6.43±1.05 mmol/L (p = 0.046)),可能是由于HDL-C升高(p < 0.001)掩盖了LDL-C的下降(p < 0.05)。甘油三酯(TG)水平没有显著变化,仍在参考范围内。结论:值得注意的是,越橘汁组动脉粥样硬化小密度低密度脂蛋白(sdLDL)亚组分显著降低,表明心血管危险因素发生了有利的变化。这些发现强调了越橘类产品作为改善超重/肥胖女性脂质谱的支持策略的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Short-Term Supplementation with 100% Bilberry Products and Its Effects on Body Composition and Lipid Profile in Overweight/Obese Women.

Introduction: Overweight and obesity are major public health concerns, often leading to increased cardiovascular risk. Methods: This eight-week interventional study examined whether regular consumption of two natural bilberry products could improve body composition and lipid profiles in overweight/obese women. A total of 30 participants (aged 50-60 years) were assigned to consume either 125 mL/day of 100% bilberry juice or 10 g/day of 100% bilberry fibre, while maintaining their habitual diets and lifestyles. Results: Although no significant changes were found in anthropometric parameters or blood pressure in either group, both interventions reduced low-density lipoprotein cholesterol (LDL-C) and increased high-density lipoprotein cholesterol (HDL-C). Surprisingly, total cholesterol (TC) levels rose in the bilberry juice group (from 6.41 ± 1.23 mmol/L to 6.94 ± 1.30 mmol/L (p < 0.001)), and in the fibre group (from 6.06 ± 1.39 mmol/L to 6.43 ± 1.05 mmol/L (p = 0.046)), likely due to elevated HDL-C (p < 0.001) overshadowing the drop in LDL-C (p < 0.05). Triglyceride (TG) levels did not change significantly and were still within the reference range. Conclusions: Notably, the bilberry juice group experienced a significant reduction in atherogenic small dense LDL (sdLDL) subfractions, suggesting a favourable shift in cardiovascular risk factors. These findings highlight the potential of bilberry-based products as a supportive strategy for improving lipid profiles in overweight/obese women.

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来源期刊
Metabolites
Metabolites Biochemistry, Genetics and Molecular Biology-Molecular Biology
CiteScore
5.70
自引率
7.30%
发文量
1070
审稿时长
17.17 days
期刊介绍: Metabolites (ISSN 2218-1989) is an international, peer-reviewed open access journal of metabolism and metabolomics. Metabolites publishes original research articles and review articles in all molecular aspects of metabolism relevant to the fields of metabolomics, metabolic biochemistry, computational and systems biology, biotechnology and medicine, with a particular focus on the biological roles of metabolites and small molecule biomarkers. Metabolites encourages scientists to publish their experimental and theoretical results in as much detail as possible. Therefore, there is no restriction on article length. Sufficient experimental details must be provided to enable the results to be accurately reproduced. Electronic material representing additional figures, materials and methods explanation, or supporting results and evidence can be submitted with the main manuscript as supplementary material.
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