Juan Luis Torres-Tenor, Eduardo Bruera, Inés Sánchez-Mañas, Teresa Pérez-Manrique, Aránzazu Castellano-Candalija, Alberto Alonso-Babarro
{"title":"姑息治疗专科门诊癌症患者非医疗阿片类药物使用的频率和风险预测因素","authors":"Juan Luis Torres-Tenor, Eduardo Bruera, Inés Sánchez-Mañas, Teresa Pérez-Manrique, Aránzazu Castellano-Candalija, Alberto Alonso-Babarro","doi":"10.1007/s12094-025-03929-7","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To assess non-medical opioid use (NMOU) risk frequency in outpatients with cancer, compare at-risk vs. non-risk patients, and evaluate the Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R) against its shortened version (SOAPP-SF).</p><p><strong>Methods: </strong>/patients. This cross-sectional study was conducted in a tertiary hospital's palliative care clinic. Adult patients with advanced cancer and cancer pain using or initiating prescribed opioids were included. Patients self-completed the SOAPP-R and SOAPP-SF during consultations. Additional data were gathered from medical records.</p><p><strong>Results: </strong>A total of 47 patients completed SOAPP-R and SOAPP-SF to assess NMOU risk, with 28% (n = 13) classified as high-risk by both. High-risk patients were younger (p = 0.003), received higher opioid doses (p = 0.026), used more substances (p = 0.018), and were more frequently employed (p = 0.001). SOAPP-SF showed 0.85 specificity, 0.6 sensitivity, 0.85 negative predictive value, and 0.6 positive predictive value compared to SOAPP-R. Both tests agreed on 61.5% of high-risk and 85% of low-risk cases.</p><p><strong>Conclusions: </strong>Among outpatients with advanced cancer, 28% had high NMOU risk, which was associated with younger age, higher opioid doses, greater substance use, and higher employment rates. SOAPP-SF retained most of the predictive power of the SOAPP-R.</p>","PeriodicalId":50685,"journal":{"name":"Clinical & Translational Oncology","volume":" ","pages":"4051-4057"},"PeriodicalIF":2.5000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Frequency and predictors of risk of non-medical opioid use among patients with cancer in a specialized outpatient palliative care clinic.\",\"authors\":\"Juan Luis Torres-Tenor, Eduardo Bruera, Inés Sánchez-Mañas, Teresa Pérez-Manrique, Aránzazu Castellano-Candalija, Alberto Alonso-Babarro\",\"doi\":\"10.1007/s12094-025-03929-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To assess non-medical opioid use (NMOU) risk frequency in outpatients with cancer, compare at-risk vs. non-risk patients, and evaluate the Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R) against its shortened version (SOAPP-SF).</p><p><strong>Methods: </strong>/patients. This cross-sectional study was conducted in a tertiary hospital's palliative care clinic. Adult patients with advanced cancer and cancer pain using or initiating prescribed opioids were included. Patients self-completed the SOAPP-R and SOAPP-SF during consultations. Additional data were gathered from medical records.</p><p><strong>Results: </strong>A total of 47 patients completed SOAPP-R and SOAPP-SF to assess NMOU risk, with 28% (n = 13) classified as high-risk by both. High-risk patients were younger (p = 0.003), received higher opioid doses (p = 0.026), used more substances (p = 0.018), and were more frequently employed (p = 0.001). SOAPP-SF showed 0.85 specificity, 0.6 sensitivity, 0.85 negative predictive value, and 0.6 positive predictive value compared to SOAPP-R. Both tests agreed on 61.5% of high-risk and 85% of low-risk cases.</p><p><strong>Conclusions: </strong>Among outpatients with advanced cancer, 28% had high NMOU risk, which was associated with younger age, higher opioid doses, greater substance use, and higher employment rates. SOAPP-SF retained most of the predictive power of the SOAPP-R.</p>\",\"PeriodicalId\":50685,\"journal\":{\"name\":\"Clinical & Translational Oncology\",\"volume\":\" \",\"pages\":\"4051-4057\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical & Translational Oncology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s12094-025-03929-7\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/4/19 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical & Translational Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s12094-025-03929-7","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/19 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
Frequency and predictors of risk of non-medical opioid use among patients with cancer in a specialized outpatient palliative care clinic.
Purpose: To assess non-medical opioid use (NMOU) risk frequency in outpatients with cancer, compare at-risk vs. non-risk patients, and evaluate the Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R) against its shortened version (SOAPP-SF).
Methods: /patients. This cross-sectional study was conducted in a tertiary hospital's palliative care clinic. Adult patients with advanced cancer and cancer pain using or initiating prescribed opioids were included. Patients self-completed the SOAPP-R and SOAPP-SF during consultations. Additional data were gathered from medical records.
Results: A total of 47 patients completed SOAPP-R and SOAPP-SF to assess NMOU risk, with 28% (n = 13) classified as high-risk by both. High-risk patients were younger (p = 0.003), received higher opioid doses (p = 0.026), used more substances (p = 0.018), and were more frequently employed (p = 0.001). SOAPP-SF showed 0.85 specificity, 0.6 sensitivity, 0.85 negative predictive value, and 0.6 positive predictive value compared to SOAPP-R. Both tests agreed on 61.5% of high-risk and 85% of low-risk cases.
Conclusions: Among outpatients with advanced cancer, 28% had high NMOU risk, which was associated with younger age, higher opioid doses, greater substance use, and higher employment rates. SOAPP-SF retained most of the predictive power of the SOAPP-R.
期刊介绍：
Clinical and Translational Oncology is an international journal devoted to fostering interaction between experimental and clinical oncology. It covers all aspects of research on cancer, from the more basic discoveries dealing with both cell and molecular biology of tumour cells, to the most advanced clinical assays of conventional and new drugs. In addition, the journal has a strong commitment to facilitating the transfer of knowledge from the basic laboratory to the clinical practice, with the publication of educational series devoted to closing the gap between molecular and clinical oncologists. Molecular biology of tumours, identification of new targets for cancer therapy, and new technologies for research and treatment of cancer are the major themes covered by the educational series. Full research articles on a broad spectrum of subjects, including the molecular and cellular bases of disease, aetiology, pathophysiology, pathology, epidemiology, clinical features, and the diagnosis, prognosis and treatment of cancer, will be considered for publication.
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