绘制压力下的大脑神经网络。

4区 医学 Q3 Neuroscience
Progress in brain research Pub Date : 2025-01-01 Epub Date: 2025-02-16 DOI:10.1016/bs.pbr.2025.01.014
Al-Hassan Soliman Wadan, Mohamed Abdelsattar Ahmed, Nasrollah Moradikor
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引用次数: 0

摘要

压力会对中枢神经系统造成严重损害,并增加患神经和精神疾病的风险。更多地了解压力的神经生物学对于治疗与压力相关的神经系统疾病至关重要,这些疾病占世界疾病负担的很大比例。然而,由于压力源类型、压力感知和之前接触压力源的复杂变化,研究压力的影响是具有挑战性的。性别、年龄和时间是影响压力反应的其他关键变量。行为、生理、遗传和细胞/分子神经科学方法都被广泛应用于各种研究环境中,以检查压力的神经生物学影响。此外,由于这些方法具有侵入性,因此不希望或不实际用于人类,因此它们经常难以适应治疗环境。作为侵入性手术的替代方法,功能性神经成像方法正在开始发展。本章讨论应激下的脑神经网络。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mapping brain neural networks in stress brain connectivity.

Stress can cause severe damage to the CNS and contribute to an increased risk of neurological and psychiatric disorders. Gaining more insight into the neurobiology of stress is essential to treating neurological disorders associated with stress, which account for a high percentage of the world's disease burden. However, because of complicated variations in stressor types, stress perception, and preceding exposure to stressors, studying the impacts of stress is challenging. Gender, age, and timing are other crucial variables that can influence the stress response. Behavioral, physiological, genetic, and cellular/molecular neuroscience methodologies have all been widely applied in various research contexts to examine the neurobiological impacts of stress. Furthermore, because these approaches are invasive and hence undesirable or impractical for use in humans, they are frequently challenging to adapt to a therapeutic context. As an alternative to invasive procedures, functional neuroimaging approaches are starting to be developed. We discuss in this chapter brain neural networks under stress brain connection.

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来源期刊
Progress in brain research
Progress in brain research 医学-神经科学
CiteScore
5.20
自引率
0.00%
发文量
174
审稿时长
6-12 weeks
期刊介绍: Progress in Brain Research is the most acclaimed and accomplished series in neuroscience. The serial is well-established as an extensive documentation of contemporary advances in the field. The volumes contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry and the behavioral sciences.
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