创伤性脑损伤住院患者癫痫发作的患病率:一项基于美国人群的研究

IF 1.8 Q3 CLINICAL NEUROLOGY
Neurotrauma reports Pub Date : 2025-04-09 eCollection Date: 2025-01-01 DOI:10.1089/neur.2025.0001
Alka Mithal, Maanek Sehgal, Christopher Newey, Derek Ems, Vince Florio, Gurkirpal Singh
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引用次数: 0

摘要

在美国,关于创伤性脑损伤(TBI)和伴随癫痫发作的成人住院治疗结果的数据有限。在这里,我们报告了一项可行性分析,以了解TBI患者并发癫痫发作的患病率和后果。采用2016-2020年全国住院患者样本进行回顾性数据库研究。对TBI患者(≥18岁)的住院情况进行评估,并将其分为伴有或不伴有癫痫发作的组。所有患者数据按年龄、性别、种族和付款人类型进行分层。主要结局是TBI住院患者中癫痫发作或癫痫的患病率。记录的其他结果变量包括平均收费、住院时间和病死率。总体而言,在研究期间评估了1,591,575例TBI住院病例。在整个研究期间,TBI患病率保持相对稳定,在男性和年龄≥65岁的人群中较高。12.2%的患者伴有癫痫发作,其中男性、45-64岁年龄组、黑人和印第安人发生率最高。在所有研究年份中,与没有癫痫发作的患者相比,有癫痫发作的TBI住院患者的平均收费明显更高,住院时间也明显更长。癫痫发作患者与无癫痫发作患者的病死率无显著差异。该分析的数据显示,TBI住院患者伴发癫痫与不伴发癫痫在人口统计学和结果上存在差异,强调了癫痫患者在医疗保健方面的潜在差异,值得进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of Seizures in Hospitalizations with Traumatic Brain Injury: A U.S. Population-Based Study.

In the United States, data on outcomes in adults hospitalized with traumatic brain injury (TBI) and concomitant seizures are limited. Here, we report on a feasibility analysis to understand the prevalence and consequences of concomitant seizures in patients with TBI. A retrospective database study was conducted using the National Inpatient Sample 2016-2020. Hospitalizations in patients (≥18 years of age) with TBI were assessed and stratified into groups either with or without concomitant seizures. All patient data were stratified by age, sex, ethnicity, and payer type. The primary outcome was the prevalence of seizures or epilepsy among hospitalizations for TBI. Other outcome variables recorded were mean charges, length of hospital stay, and case fatality. Overall, 1,591,575 hospitalizations with TBI were assessed over the study period. TBI prevalence remained relatively constant throughout the study period and was higher in men and those aged ≥65 years. Concomitant seizures were observed in 12.2% of all patients and were highest for men, the 45-64 years age group, and Black and Native Americans. Mean charges were significantly higher and length of hospital stay was significantly longer in TBI hospitalizations with seizures compared with those without seizures across all study years. No significant difference in case fatality between patients with seizures compared with those without seizures was observed. Data from this analysis showed differences in demographics and outcomes for TBI hospitalizations with versus without concomitant seizures, highlighting potential disparities in health care for patients experiencing seizures that warrant further research.

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CiteScore
2.40
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