数字光处理(DLP)生物打印的进展:生物材料及其应用、创新、挑战和未来展望

IF 4.7 3区 工程技术 Q1 POLYMER SCIENCE
Polymers Pub Date : 2025-05-07 DOI:10.3390/polym17091287
Cem Alparslan, Şenol Bayraktar
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引用次数: 0

摘要

数字光处理(DLP)技术作为生物医学工程领域的一种突破性方法,能够使用光聚合材料生产高精度结构。形状记忆聚合物、水凝胶和纳米复合材料等智能材料由于其在DLP技术中具有优异的机械强度、生物相容性和对环境刺激的敏感性等特性,被用作个性化医疗应用的理想材料。这些材料与DLP的集成使功能和复杂结构的生产成为可能,特别是在骨和软组织工程、药物输送和生物传感器生产等领域。然而,有限的材料多样性、生产过程中的可扩展性问题以及优化生物打印参数的技术困难是该领域的主要障碍。本研究系统地考察了智能生物材料在基于dlp的生物打印过程中的作用。它解决了这些材料在组织工程和再生医学中的创新应用。它还全面评估其对生物医学应用的贡献,并讨论未来的研究领域,以克服当前的局限性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Advances in Digital Light Processing (DLP) Bioprinting: A Review of Biomaterials and Its Applications, Innovations, Challenges, and Future Perspectives.

Digital light processing (DLP) technology stands out as a groundbreaking method in the field of biomedical engineering that enables the production of highly precise structures using photopolymerizable materials. Smart materials such as shape memory polymers, hydrogels, and nanocomposites are used as ideal materials for personalized medicine applications thanks to their properties such as superior mechanical strength, biocompatibility, and sensitivity to environmental stimuli in DLP technology. The integration of these materials with DLP enables the production of functional and complex structures, especially in areas such as bone and soft tissue engineering, drug delivery, and biosensor production. However, limited material diversity, scalability problems in production processes, and technical difficulties in optimizing bioprinting parameters are among the main obstacles in this field. This study systematically examines the role of smart biomaterials in DLP-based bioprinting processes. It addresses the innovative applications of these materials in tissue engineering and regenerative medicine. It also comprehensively evaluates its contributions to biomedical applications and discusses future research areas to overcome current limitations.

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来源期刊
Polymers
Polymers POLYMER SCIENCE-
CiteScore
8.00
自引率
16.00%
发文量
4697
审稿时长
1.3 months
期刊介绍: Polymers (ISSN 2073-4360) is an international, open access journal of polymer science. It publishes research papers, short communications and review papers. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. Therefore, there is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Polymers provides an interdisciplinary forum for publishing papers which advance the fields of (i) polymerization methods, (ii) theory, simulation, and modeling, (iii) understanding of new physical phenomena, (iv) advances in characterization techniques, and (v) harnessing of self-assembly and biological strategies for producing complex multifunctional structures.
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