突尼斯患者骨巨细胞瘤的手术治疗方法:与复发的关系。

IF 1.8 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Libyan Journal of Medicine Pub Date : 2025-12-01 Epub Date: 2025-04-24 DOI:10.1080/19932820.2025.2494885
Raja Amri, Mariam Ayedi, Sami Aifa, Hassib Keskes
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引用次数: 0

摘要

骨巨细胞瘤(GCTB)通常被认为是一种良性肿瘤,但它可以表现出局部侵袭性行为。GCTB的两种主要手术治疗选择是病灶内刮除和整体切除。本研究调查了突尼斯手术后GCTB患者的长期复发率。对36例确诊为GCTB的患者进行了研究。这些患者接受了外科手术,特别是病灶内刮除和整体切除。随后,我们对这些患者进行了两年的术后监测。统计分析包括Kaplan-Meier生存分析、Cox比例风险回归和卡方检验,以确定和评估与局部复发相关的因素。我们的分析显示手术治疗与局部复发率之间有显著的关联
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surgical approaches for the treatment of giant cell tumor of bone in Tunisian patients: association with recurrence.

Giant cell tumor of bone (GCTB) is generally considered a benign tumor, but it can exhibit locally aggressive behavior. The two main surgical treatment options for GCTB are intralesional curettage and en-bloc resection. This study examined the long-term GCTB recurrence rates among Tunisian patients after surgery. A study including 36 patients diagnosed with GCTB was conducted. These patients underwent surgical procedures, specifically intralesional curettage and in bloc resection. Subsequently, we monitored these patients for a two-year post-operative period. Statistical analyses, including Kaplan-Meier survival analysis, Cox proportional hazards regression, and chi-square tests, were performed to identify and evaluate factors associated with local recurrence. Our analysis showed a significant association between surgical treatment and the occurrence of local recurrence (p < 0.01). Interestingly, the rate of local recurrence was notably higher among patients who underwent intralesional curettage (13 out of 21; 61%) compared to those who received en bloc resection (2 out of 15; 13%) (all p < 0.01). En-bloc resection is a reliable treatment choice for GCTB, demonstrating a lower risk of recurrence compared to intralesional curettage. These findings highlight the importance of selecting the appropriate surgical approach to minimize recurrence and improve patient outcomes.

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来源期刊
Libyan Journal of Medicine
Libyan Journal of Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
3.50
自引率
4.20%
发文量
20
审稿时长
>12 weeks
期刊介绍: Libyan Journal of Medicine (LJM) is a peer-reviewed, Open Access, international medical journal aiming to promote heath and health education by publishing high-quality medical research in the different disciplines of medicine. LJM was founded in 2006 by a group of enthusiastic Libyan medical scientists who looked at the contribution of Libyan publications to the international medical literature and saw that a publication outlet was missing. To fill this gap they launched LJM as a tool for transferring current medical knowledge to and from colleagues in developing countries, particularly African countries, as well as internationally.The journal is still led by a group of Libyan physicians inside and outside Libya, but it also enjoys support and recognition from the international medical community.
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