[戊型肝炎：流行病学、病理学和预防]。

IF 0.6 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

M S-medecine Sciences Pub Date : 2025-04-01 Epub Date: 2025-04-28 DOI:10.1051/medsci/2025047

Nancy León-Janampa, Denys Brand, Julien Marlet

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引用次数: 0

摘要

戊型肝炎病毒（HEV）是急性肝炎的主要病因。HEV基因型1和2与孕妇的口-粪便流行和暴发性肝炎有关。HEV基因型3和4是由生猪肉传播的人畜共患病。感染通常会自行消退。慢性肝炎可能发生在免疫功能低下的患者身上。肝外疾病也是可能的。预防的基础是卫生，特别是高危患者的卫生，以及所有人都能获得安全饮用水。一种针对戊肝病毒的重组疫苗已经开发出来，目前正在由世卫组织进行验证。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Hepatitis E: Epidemiology, pathology and prevention].

Hepatitis E virus (HEV) is a major cause of acute hepatitis. HEV genotypes 1 and 2 are associated with oro-faecal epidemics and fulminant hepatitis in pregnant women. HEV genotypes 3 and 4 are a zoonosis transmitted by uncooked pork. Infection is usually spontaneously resolutive. Chronic hepatitis may occur in immunocompromised patients. Extrahepatic disease is also possible. Prevention is based on hygiene, especially in high-risk patients, and access to safe drinking water for all. A recombinant vaccine against HEV has been developed and is currently being validated by the WHO.

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来源期刊

M S-medecine Sciences 医学-医学：研究与实验

CiteScore

0.80

自引率

14.30%

发文量

182

审稿时长

4-8 weeks

期刊介绍： m/s offers high-quality review articles in French, covering all areas of biomedical and health research, in a monthly magazine format (10 issues / year). m/s is read by the whole French-speaking community, in France but also in Belgium, Switzerland, Canada, Morocco, Algeria, Tunisia etc. m/s is not a primary publication, and thus will not consider unpublished data. Most articles are invited by the Editors, but spontaneous proposals are welcomed. Each issue combines news and views on the most recent scientific publications, as well as broadly accessible and updated review articles on a specific topic, and essays on science and society, history of science, public health, or reactions to published articles. Each year, m/s also publishes one or two thematic issues focused on a research topic of high interest. All review articles and essays are peer-reviewed.