应用关节镜和自体脂肪移植术治疗基底关节关节炎。

IF 1.5 Q3 SURGERY
Plastic and Reconstructive Surgery Global Open Pub Date : 2025-04-24 eCollection Date: 2025-04-01 DOI:10.1097/GOX.0000000000006720
Peter Deptula, Meghan McCullough, Theodore Brown, Dylan Singh, Kylie Tanabe, Eugene Tsai, David Kulber
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引用次数: 0

摘要

背景:先前的研究表明,与寰椎切除术相比,关节内注射自体脂肪可能是治疗腕掌关节关节炎的一种可行的、侵入性较小的方法。小关节镜检查也被发现是评估和治疗关节炎的有用工具。作者提出一种关节镜下微创清创联合自体脂肪移植术和富血小板血浆(PRP)注射治疗CMC关节炎的方法。方法:Eaton II-IV期CMC骨关节炎患者行关节镜清创,关节内注射自体脂肪和PRP。评估术前和术后疼痛评分、功能结果、关节半脱位的影像学改善、患者满意度和并发症。结果:行拇指CMC关节镜下脂肪移植术和PRP术48例。术中及术后均无直接并发症。没有患者需要翻修手术。术前活动时的平均疼痛评分从8.9±0.9提高到3.3±2.2 (P < 0.0001),休息时的平均疼痛评分从5.0±2.5提高到1.0±1.3 (P < 0.0001)。采用M1M2重叠测量射线沉降。从术前4.4±2.8 mm改善到术后6.8±2.3 mm,相对改善70% (P < 0.0042)。患者满意度高。结论:关节镜技术联合自体脂肪和PRP治疗CMC关节疼痛和关节半脱位是有效的。其他的前瞻性研究正在进行中,以比较传统的关节置换技术,并评估该技术在其他小关节病理中的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Preservation Arthroplasty for Basal Joint Arthritis Using Arthroscopy and Autologous Fat Grafting With Platelet-rich Plasma.

Background: Prior studies have shown that intra-articular injection of autologous fat may be a viable, less invasive approach for the treatment of carpometacarpal (CMC) joint arthritis, compared with trapeziecetomy. Small joint arthroscopy has also been found to be a useful tool in evaluation and treatment of arthritis. The authors present a treatment for CMC arthritis combining a minimally invasive approach for arthroscopic debridement with autologous fat grafting and platelet-rich plasma (PRP) injection.

Methods: Patients with Eaton stage II-IV CMC osteoarthritis underwent arthroscopic debridement and injection of autologous fat and PRP into the joint. Pre- and postoperative pain scores, functional outcomes, radiographic improvement in joint subluxation, patient satisfaction, and complications were evaluated.

Results: Forty-eight thumb CMC joint arthroscopies with fat grafting and PRP were performed. No intraoperative or immediate postoperative complications were experienced. No patients required revision surgery. Average preoperative pain scores with activity improved from 8.9 ± 0.9 to 3.3 ± 2.2 (P < 0.0001) and at rest improved from 5.0 ± 2.5 to 1.0 ± 1.3 (P < 0.0001). M1M2 overlap was used to measure radiographic subsidence. This improved from 4.4 ± 2.8 mm preoperatively to 6.8 ± 2.3 mm postoperatively, reflecting a relative improvement of 70% (P < 0.0042). High patient satisfaction was noted.

Conclusions: Treatment of the CMC joint using arthroscopic technique combined with autologous fat and PRP is effective in treating pain and joint subluxation. Additional prospective studies are underway for comparison to traditional arthroplasty techniques and to evaluate this technique's potential for other small joint pathology.

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来源期刊
CiteScore
2.20
自引率
13.30%
发文量
1584
审稿时长
10 weeks
期刊介绍: Plastic and Reconstructive Surgery—Global Open is an open access, peer reviewed, international journal focusing on global plastic and reconstructive surgery.Plastic and Reconstructive Surgery—Global Open publishes on all areas of plastic and reconstructive surgery, including basic science/experimental studies pertinent to the field and also clinical articles on such topics as: breast reconstruction, head and neck surgery, pediatric and craniofacial surgery, hand and microsurgery, wound healing, and cosmetic and aesthetic surgery. Clinical studies, experimental articles, ideas and innovations, and techniques and case reports are all welcome article types. Manuscript submission is open to all surgeons, researchers, and other health care providers world-wide who wish to communicate their research results on topics related to plastic and reconstructive surgery. Furthermore, Plastic and Reconstructive Surgery—Global Open, a complimentary journal to Plastic and Reconstructive Surgery, provides an open access venue for the publication of those research studies sponsored by private and public funding agencies that require open access publication of study results. Its mission is to disseminate high quality, peer reviewed research in plastic and reconstructive surgery to the widest possible global audience, through an open access platform. As an open access journal, Plastic and Reconstructive Surgery—Global Open offers its content for free to any viewer. Authors of articles retain their copyright to the materials published. Additionally, Plastic and Reconstructive Surgery—Global Open provides rapid review and publication of accepted papers.
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