基于孔径的复杂性指标分析及其对调强放疗计划中患者特异性质量保证的影响。

IF 0.7 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Physics Pub Date : 2025-01-01 Epub Date: 2025-03-24 DOI:10.4103/jmp.jmp_195_24

Dinesh Kumar Saroj, Suresh Yadav, Neetu Paliwal, Ravindra Bhagwat Shende, Gaurav Gupta

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引用次数: 0

摘要

背景：通过复杂性度量来识别存在患者特定质量保证（PSQA）失败风险的计划可以在保持质量的同时减少工作量。本研究评估复杂性指标作为PSQA结果的预测因子。材料与方法：回顾性分析192例头颈癌IMRT治疗方案。复杂度指标是使用内部Python程序计算的。PSQA采用3%/ 2mm伽玛通过率（GPR）标准，计划分为“通过”（GPR≥95%）或“失败”。统计分析，包括Spearman相关分析和受者工作特征分析，评估指标的预测价值。结果：通过计划的平均探地雷达为98.64±1.33%，失败计划的平均探地雷达为92.17±2.35%。平均小面积段（MSAS） 5mm，阈值为0.085，真阳性率为38.17%，假阳性率为3.1%。波束调制和波束面积指数在通过和失败方案之间也有显著差异。结论：MSAS5和边缘指标显示了识别高风险计划的强大潜力。这些指标可以指导有针对性的PSQA，在不影响处理安全性的情况下提高工作流程效率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Analysis of Aperture-based Complexity Metrics and Their Effect on Patient-specific Quality Assurance in Intensity-modulated Radiation Therapy Planning.

Background: Identifying plans at risk of patient-specific quality assurance (PSQA) failure through complexity metrics can reduce the workload while maintaining quality. This study evaluates complexity metrics as predictors of PSQA outcomes.

Materials and methods: A retrospective analysis was conducted on 192 IMRT plans for head-and-neck cancer. Complexity metrics were calculated using an in-house Python program. PSQA was performed with 3%/2-mm gamma passing rate (GPR) criteria, with plans classified as "Pass" (GPR ≥95%) or "Fail." Statistical analyses, including Spearman's correlation and receiver operating characteristic analysis, assessed the metrics' predictive value.

Results: Passing plans had an average GPR of 98.64 ± 1.33%, compared to 92.17 ± 2.35% for failing plans. The mean small area segment (MSAS) 5mm metric, with a threshold of 0.085, achieved a true positive rate of 38.17% and a false positive rate of 3.1%. Beam modulation and beam area indices also significantly differed between passing and failing plans.

Conclusion: MSAS5 and edge metrics showed strong potential for identifying high-risk plans. These metrics can guide targeted PSQA, improving workflow efficiency without compromising treatment safety.

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来源期刊

Journal of Medical Physics RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

1.10

自引率

11.10%

发文量

审稿时长

30 weeks

期刊介绍： JOURNAL OF MEDICAL PHYSICS is the official journal of Association of Medical Physicists of India (AMPI). The association has been bringing out a quarterly publication since 1976. Till the end of 1993, it was known as Medical Physics Bulletin, which then became Journal of Medical Physics. The main objective of the Journal is to serve as a vehicle of communication to highlight all aspects of the practice of medical radiation physics. The areas covered include all aspects of the application of radiation physics to biological sciences, radiotherapy, radiodiagnosis, nuclear medicine, dosimetry and radiation protection. Papers / manuscripts dealing with the aspects of physics related to cancer therapy / radiobiology also fall within the scope of the journal.