Olivier Cusson, Mira Liebman, Robert J Klaassen, Brianna Mckelvie
{"title":"脾栓塞治疗原发性免疫性血小板减少症合并颅内出血2例报告。","authors":"Olivier Cusson, Mira Liebman, Robert J Klaassen, Brianna Mckelvie","doi":"10.1097/MPH.0000000000003029","DOIUrl":null,"url":null,"abstract":"<p><p>This case report describes the management of 2 pediatric patients with immune thrombocytopenia (ITP) complicated by intracranial hemorrhage. Case 1 involves a 16-year-old who was found to have an acute intracerebral bleed. Partial splenic embolization was performed, which led to improved platelet count and clinical stability. Case 2 details an 8-year-old presenting with a large frontal hematoma with clinical and radiologic signs of herniation. Following complete splenic embolization, his platelet levels rose sufficiently to undergo a successful craniectomy. These cases emphasize the potential role of splenic embolization as an innovative intervention in cases of pediatric ITP with life-threatening bleeding.</p>","PeriodicalId":16693,"journal":{"name":"Journal of Pediatric Hematology/Oncology","volume":"47 4","pages":"214-217"},"PeriodicalIF":0.9000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Splenic Embolization for Primary Immune Thrombocytopenia Complicated With Intracranial Hemorrhage-Case Report of 2 Patients.\",\"authors\":\"Olivier Cusson, Mira Liebman, Robert J Klaassen, Brianna Mckelvie\",\"doi\":\"10.1097/MPH.0000000000003029\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This case report describes the management of 2 pediatric patients with immune thrombocytopenia (ITP) complicated by intracranial hemorrhage. Case 1 involves a 16-year-old who was found to have an acute intracerebral bleed. Partial splenic embolization was performed, which led to improved platelet count and clinical stability. Case 2 details an 8-year-old presenting with a large frontal hematoma with clinical and radiologic signs of herniation. Following complete splenic embolization, his platelet levels rose sufficiently to undergo a successful craniectomy. These cases emphasize the potential role of splenic embolization as an innovative intervention in cases of pediatric ITP with life-threatening bleeding.</p>\",\"PeriodicalId\":16693,\"journal\":{\"name\":\"Journal of Pediatric Hematology/Oncology\",\"volume\":\"47 4\",\"pages\":\"214-217\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pediatric Hematology/Oncology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/MPH.0000000000003029\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/4/22 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"HEMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pediatric Hematology/Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/MPH.0000000000003029","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/22 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"HEMATOLOGY","Score":null,"Total":0}
Splenic Embolization for Primary Immune Thrombocytopenia Complicated With Intracranial Hemorrhage-Case Report of 2 Patients.
This case report describes the management of 2 pediatric patients with immune thrombocytopenia (ITP) complicated by intracranial hemorrhage. Case 1 involves a 16-year-old who was found to have an acute intracerebral bleed. Partial splenic embolization was performed, which led to improved platelet count and clinical stability. Case 2 details an 8-year-old presenting with a large frontal hematoma with clinical and radiologic signs of herniation. Following complete splenic embolization, his platelet levels rose sufficiently to undergo a successful craniectomy. These cases emphasize the potential role of splenic embolization as an innovative intervention in cases of pediatric ITP with life-threatening bleeding.
期刊介绍:
Journal of Pediatric Hematology/Oncology (JPHO) reports on major advances in the diagnosis and treatment of cancer and blood diseases in children. The journal publishes original research, commentaries, historical insights, and clinical and laboratory observations.