Respiratory symptom cluster in people with lung cancer.

Purpose of review: Respiratory symptoms often co-occur as a symptom cluster in lung cancer patients, which can be detrimental to clinical outcomes. This review synthesizes recent evidence on respiratory symptom clusters and their management.

Recent findings: The expanding body of evidence on respiratory symptom clusters in lung cancer patients has grown significantly. These clusters, primarily comprising cough, shortness of breath, and expectoration, remain prevalent and persistent, regardless of treatment modalities. Cough is highlighted as the sentinel symptom. Recent advancements, including both multimodal and single-component non-pharmacological interventions, such as the Respiratory Distress Symptom Intervention and acupuncture, have shown promise in alleviating respiratory symptoms.

Summary: Recent studies have significantly advanced our understanding of identifying and managing respiratory symptom clusters in lung cancer patients. Longitudinal studies tracking respiratory symptoms could provide valuable insights into their progression. This could be achieved by integrating advanced technologies, such as mobile health applications, which have the potential to revolutionize real-time symptom monitoring. Furthermore, understanding the biological mechanisms underlying these clusters is essential for developing targeted therapies that address symptoms more comprehensively.