当口腔健康影响整体健康:生物膜,牙齿感染和新兴的抗菌策略。

IF 5.4 2区 医学 Q1 INFECTIOUS DISEASES
Ahmed Adel Abdelaziz, Ahmed S Doghish, Akram N Salah, Reda M Mansour, Yasser M Moustafa, Sherif S Abdel Mageed, Hebatallah Ahmed Mohamed Moustafa, Walaa A El-Dakroury, Sama A Doghish, Osama A Mohammed, Mustafa Ahmed Abdel-Reheim, Shaimaa O Abbass, Sara O Abbass, Mariam O Abbass, Amira Mohamed Samy, Mahmoud A Elrebehy, Youssef A Doghish
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引用次数: 0

摘要

牙齿健康是整体健康的重要组成部分,但在关于健康的讨论中经常被忽视。本文探讨了牙齿感染的多方面,主要集中在致病细菌如变形链球菌和牙龈卟啉单胞菌形成的生物膜上。这些生物膜会导致龋齿和牙周病,影响口腔健康并产生全身后果。在了解生物膜形成和相互作用方面的最新进展导致了新的预防和治疗策略,包括使用纳米颗粒和智能水凝胶来破坏生物膜的完整性,同时促进与人体组织的生物相容性。此外,文章强调了自然疗法的潜力,包括草药提取物,作为维持口腔卫生和对抗微生物感染的辅助手段。全面概述了生物膜动力学,包括粘附,成熟和分散,同时讨论了创新的治疗方法,解决了传统治疗的局限性。最后,这篇文章强调了保持牙齿健康在预防一系列健康问题中的重要性,强调了口腔是通往身体的门户。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
When oral health affects overall health: biofilms, dental infections, and emerging antimicrobial strategies.

Dental health is a crucial component of overall health, yet it is frequently overlooked in discussions about well-being. This article explores the multifaceted aspects of dental infections, primarily focusing on biofilms formed by pathogenic bacteria such as Streptococcus mutans and Porphyromonas gingivalis. These biofilms contribute to dental caries and periodontal disease, conditions that affect oral health and have systemic consequences. Recent advancements in understanding biofilm formation and interactions have led to novel strategies for prevention and treatment, including using nanoparticles and smart hydrogels designed to disrupt biofilm integrity while promoting biocompatibility with human tissues. Furthermore, the article highlights the potential of natural remedies, including herbal extracts, as adjuncts in maintaining oral hygiene and combating microbial infections. A comprehensive overview of biofilm dynamics, including adhesion, maturation, and dispersion, is presented, alongside discussions on innovative therapeutic approaches addressing the limitations of conventional treatments. Ultimately, this article emphasizes the importance of maintaining dental health in preventing a wide spectrum of health issues, reinforcing that the mouth is a gateway to the body.

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来源期刊
Infection
Infection 医学-传染病学
CiteScore
12.50
自引率
1.30%
发文量
224
审稿时长
6-12 weeks
期刊介绍: Infection is a journal dedicated to serving as a global forum for the presentation and discussion of clinically relevant information on infectious diseases. Its primary goal is to engage readers and contributors from various regions around the world in the exchange of knowledge about the etiology, pathogenesis, diagnosis, and treatment of infectious diseases, both in outpatient and inpatient settings. The journal covers a wide range of topics, including: Etiology: The study of the causes of infectious diseases. Pathogenesis: The process by which an infectious agent causes disease. Diagnosis: The methods and techniques used to identify infectious diseases. Treatment: The medical interventions and strategies employed to treat infectious diseases. Public Health: Issues of local, regional, or international significance related to infectious diseases, including prevention, control, and management strategies. Hospital Epidemiology: The study of the spread of infectious diseases within healthcare settings and the measures to prevent nosocomial infections. In addition to these, Infection also includes a specialized "Images" section, which focuses on high-quality visual content, such as images, photographs, and microscopic slides, accompanied by brief abstracts. This section is designed to highlight the clinical and diagnostic value of visual aids in the field of infectious diseases, as many conditions present with characteristic clinical signs that can be diagnosed through inspection, and imaging and microscopy are crucial for accurate diagnosis. The journal's comprehensive approach ensures that it remains a valuable resource for healthcare professionals and researchers in the field of infectious diseases.
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