{"title":"温控射频治疗外阴硬化地衣的结果：一项初步研究。","authors":"Nengxiu Wu, Ying Li, Chaoqin Lin","doi":"10.1002/lsm.70016","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objective</h3>\n \n <p>This study aimed to evaluate the efficacy and safety of transcutaneous temperature-controlled radiofrequency (TTCRF) in the treatment of female vulvar lichen sclerosus (VLS).</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>A retrospective analysis was conducted on VLS patients treated with TTCRF at our hospital between May 2021 and May 2023. Each patient underwent ten TTCRF sessions, spaced 1 week apart. Complications were monitored throughout the treatment, and efficacy was assessed using the Cattaneo scoring system and the Patient Global Impression of Change (PGI-C) questionnaire at 1 and 6 months Posttreatment.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>A total of 40 patients were included in the study, with a mean age of 44.98 ± 11.14 years and a mean BMI of 22.78 ± 2.62 kg/m². Follow-up results at 1 and 6 months Posttreatment showed significant improvements in pruritus degree, skin elasticity, and skin color compared to baseline (<i>p</i> < 0.05), although no significant change in lesion scope was observed. According to the PGI-C questionnaire, 75% (30/40) of patients reported improvement or significant improvement at 1 month Posttreatment, which decreased to 60% (24/40) at 6 months. No adverse reactions were reported during the treatment or follow-up periods.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>TTCRF is an effective and safe treatment for female VLS, offering significant short-term symptom relief. However, further research is needed to confirm long-term benefits.</p>\n </section>\n </div>","PeriodicalId":17961,"journal":{"name":"Lasers in Surgery and Medicine","volume":"57 5","pages":"383-388"},"PeriodicalIF":2.2000,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Outcomes of Temperature-Controlled Radiofrequency in Treating Vulvar Lichen Sclerosus: A Pilot Study\",\"authors\":\"Nengxiu Wu, Ying Li, Chaoqin Lin\",\"doi\":\"10.1002/lsm.70016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objective</h3>\\n \\n <p>This study aimed to evaluate the efficacy and safety of transcutaneous temperature-controlled radiofrequency (TTCRF) in the treatment of female vulvar lichen sclerosus (VLS).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>A retrospective analysis was conducted on VLS patients treated with TTCRF at our hospital between May 2021 and May 2023. Each patient underwent ten TTCRF sessions, spaced 1 week apart. Complications were monitored throughout the treatment, and efficacy was assessed using the Cattaneo scoring system and the Patient Global Impression of Change (PGI-C) questionnaire at 1 and 6 months Posttreatment.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>A total of 40 patients were included in the study, with a mean age of 44.98 ± 11.14 years and a mean BMI of 22.78 ± 2.62 kg/m². Follow-up results at 1 and 6 months Posttreatment showed significant improvements in pruritus degree, skin elasticity, and skin color compared to baseline (<i>p</i> < 0.05), although no significant change in lesion scope was observed. According to the PGI-C questionnaire, 75% (30/40) of patients reported improvement or significant improvement at 1 month Posttreatment, which decreased to 60% (24/40) at 6 months. No adverse reactions were reported during the treatment or follow-up periods.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>TTCRF is an effective and safe treatment for female VLS, offering significant short-term symptom relief. However, further research is needed to confirm long-term benefits.</p>\\n </section>\\n </div>\",\"PeriodicalId\":17961,\"journal\":{\"name\":\"Lasers in Surgery and Medicine\",\"volume\":\"57 5\",\"pages\":\"383-388\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-04-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Lasers in Surgery and Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/lsm.70016\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lasers in Surgery and Medicine","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/lsm.70016","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DERMATOLOGY","Score":null,"Total":0}
Outcomes of Temperature-Controlled Radiofrequency in Treating Vulvar Lichen Sclerosus: A Pilot Study
Objective
This study aimed to evaluate the efficacy and safety of transcutaneous temperature-controlled radiofrequency (TTCRF) in the treatment of female vulvar lichen sclerosus (VLS).
Methods
A retrospective analysis was conducted on VLS patients treated with TTCRF at our hospital between May 2021 and May 2023. Each patient underwent ten TTCRF sessions, spaced 1 week apart. Complications were monitored throughout the treatment, and efficacy was assessed using the Cattaneo scoring system and the Patient Global Impression of Change (PGI-C) questionnaire at 1 and 6 months Posttreatment.
Results
A total of 40 patients were included in the study, with a mean age of 44.98 ± 11.14 years and a mean BMI of 22.78 ± 2.62 kg/m². Follow-up results at 1 and 6 months Posttreatment showed significant improvements in pruritus degree, skin elasticity, and skin color compared to baseline (p < 0.05), although no significant change in lesion scope was observed. According to the PGI-C questionnaire, 75% (30/40) of patients reported improvement or significant improvement at 1 month Posttreatment, which decreased to 60% (24/40) at 6 months. No adverse reactions were reported during the treatment or follow-up periods.
Conclusion
TTCRF is an effective and safe treatment for female VLS, offering significant short-term symptom relief. However, further research is needed to confirm long-term benefits.
期刊介绍：
Lasers in Surgery and Medicine publishes the highest quality research and clinical manuscripts in areas relating to the use of lasers in medicine and biology. The journal publishes basic and clinical studies on the therapeutic and diagnostic use of lasers in all the surgical and medical specialties. Contributions regarding clinical trials, new therapeutic techniques or instrumentation, laser biophysics and bioengineering, photobiology and photochemistry, outcomes research, cost-effectiveness, and other aspects of biomedicine are welcome. Using a process of rigorous yet rapid review of submitted manuscripts, findings of high scientific and medical interest are published with a minimum delay.
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