Comparison of Heidelberg Multi-Color Anomaloskop with NEITZ anomaloscope OT-II to diagnose color-vision deficiency.

Purpose: To determine the degree of agreement between the results of the Heidelberg Multi-Color Anomaloskop (HMC) and NEITZ anomaloscope OT-II (OT-II).

Study design: Retrospective.

Methods: The study included 53 patients who underwent color-vision testing at Kariya Toyota General Hospital between March 2019 and April 2022. The participants included 2 patients with normal color vision, 10 with protanopia, 3 with protanomaly, 22 with deuteranopia, and 16 with deuteranomaly. Color-vision testing was performed using the Ishihara Test for Colour Deficiency, Standard Pseudoisochromatic Plates Part 1, Farnsworth Dichotomous Test for Color Blindness Panel-15, HMC, and OT-II. An agreement was determined using intraclass correlation coefficients (ICC) and Bland-Altman analysis. The minimum, median, and maximum red-green mixture and yellow monochromatic values of the equal values obtained from HMC and OT-II were examined.

Results: The ICCs between the results of HMC and OT-II were 0.979, 0.979, and 0.985, for the minimum, median, and maximum red-green mixture and 0.943, 0.755, and 0.919 for the yellow monochromatic values, respectively (p < 0.0001 in all). In the Bland-Altman analysis, the differences were mostly within the limits of agreement. Fixed errors were observed for the maximum red-green mixture and minimum yellow monochromatic values. Proportional errors were observed for the maximum red-green mixture and yellow monochromatic values.

Conclusions: HMC and OT-II showed high agreement for all values in the ICC and Bland-Altman analyses. In the Bland-Altman analysis, systemic errors were observed in the maximum red-green mixture value and the minimum and maximum yellow monochromatic values.