{"title":"[针刺治疗脑卒中后中枢性面瘫的临床疗效和安全性：系统综述和meta分析]。","authors":"Xi-Rui Wang, Yuan-Yuan Wu, Yue-Rong Chen, Si-Yuan Tong, Jun-Yi Wang, Zong-Lin Wu, Jin-Zhu Gao","doi":"10.13702/j.1000-0607.20240426","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To systematically evaluate the efficacy and safety of acupuncture therapy in the treatment of central facial palsy after stroke.</p><p><strong>Methods: </strong>A computerized search of articles on acupuncture treatment of central facial palsy was conducted from databases of China National Knowledge Infrastructure(CNKI), Wanfang Data Knowledge Service Platform (Wanfang), VIP Information Chinese Journal Service Platform (VIP) , China Biomedical Literature Database(CBM), Cochrane Library, PubMed, Embase and Web of Science from their inception to September 25<sup>th</sup>, 2023. The Cochrane risk of bias assessment tool was used to evaluate the risk of bias of all the included literature, and Meta-analysis on the extracted data was conducted using Review Manager 5.4 software.</p><p><strong>Results: </strong>Eleven studies with a total of 893 patients were finally included, and the bias risks of the included studies were all \"some concerns\". The results of Meta-analysis suggested that:1) the observation group was superior to the control group in improving the the House-Brackmann facial nerve grading system (H-B) scores (<i>MD</i>=6.41, 95%<i>CI</i> [3.69, 9.14], <i>Z</i>=4.62, <i>P</i><0.000 01), facial disability index (FDI) scores (somatic function) (<i>MD</i>=2.72, 95%<i>CI</i> [0.31, 5.12], <i>Z</i>=2.21, <i>P</i>=0.03), and clinical effective rate (<i>RR</i>=1.25, 95%<i>CI</i> [1.15, 1.35], <i>Z</i>=5.57, <i>P</i><0.000 01);2) the observation group was not significantly different from the control group in improving the Toronto facial nerve assessment system (TFGS) scores (<i>MD</i>=3.66, 95%<i>CI</i> [ -2.33, 9.65], <i>Z</i>=1.20, <i>P</i>=0.23), the degrees of facial nerve paralysis (DFNP) scores (<i>MD</i>=4.60, 95%<i>CI</i> [ -1.14, 10.34], <i>Z</i>=1.57, <i>P</i>=0.12), FDI scores (social function) (<i>MD</i>=3.00, 95%<i>CI</i> [ -0.67, 6.66], <i>Z</i>=1.60, <i>P</i>=0.11).</p><p><strong>Conclusions: </strong>Acupuncture therapy has advantages in clinical efficacy and safety than conventional drugs and other sports rehabilitation therapies in improving post-stroke central facial palsy. However, more high-quality clinical trials are warranted to provide adequate clinical evidence.</p>","PeriodicalId":34919,"journal":{"name":"针刺研究","volume":"50 4","pages":"467-476"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Clinical efficacy and safety of acupuncture therapy for central facial palsy after stroke: a systematic review and Meta-analysis].\",\"authors\":\"Xi-Rui Wang, Yuan-Yuan Wu, Yue-Rong Chen, Si-Yuan Tong, Jun-Yi Wang, Zong-Lin Wu, Jin-Zhu Gao\",\"doi\":\"10.13702/j.1000-0607.20240426\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>To systematically evaluate the efficacy and safety of acupuncture therapy in the treatment of central facial palsy after stroke.</p><p><strong>Methods: </strong>A computerized search of articles on acupuncture treatment of central facial palsy was conducted from databases of China National Knowledge Infrastructure(CNKI), Wanfang Data Knowledge Service Platform (Wanfang), VIP Information Chinese Journal Service Platform (VIP) , China Biomedical Literature Database(CBM), Cochrane Library, PubMed, Embase and Web of Science from their inception to September 25<sup>th</sup>, 2023. The Cochrane risk of bias assessment tool was used to evaluate the risk of bias of all the included literature, and Meta-analysis on the extracted data was conducted using Review Manager 5.4 software.</p><p><strong>Results: </strong>Eleven studies with a total of 893 patients were finally included, and the bias risks of the included studies were all \\\"some concerns\\\". The results of Meta-analysis suggested that:1) the observation group was superior to the control group in improving the the House-Brackmann facial nerve grading system (H-B) scores (<i>MD</i>=6.41, 95%<i>CI</i> [3.69, 9.14], <i>Z</i>=4.62, <i>P</i><0.000 01), facial disability index (FDI) scores (somatic function) (<i>MD</i>=2.72, 95%<i>CI</i> [0.31, 5.12], <i>Z</i>=2.21, <i>P</i>=0.03), and clinical effective rate (<i>RR</i>=1.25, 95%<i>CI</i> [1.15, 1.35], <i>Z</i>=5.57, <i>P</i><0.000 01);2) the observation group was not significantly different from the control group in improving the Toronto facial nerve assessment system (TFGS) scores (<i>MD</i>=3.66, 95%<i>CI</i> [ -2.33, 9.65], <i>Z</i>=1.20, <i>P</i>=0.23), the degrees of facial nerve paralysis (DFNP) scores (<i>MD</i>=4.60, 95%<i>CI</i> [ -1.14, 10.34], <i>Z</i>=1.57, <i>P</i>=0.12), FDI scores (social function) (<i>MD</i>=3.00, 95%<i>CI</i> [ -0.67, 6.66], <i>Z</i>=1.60, <i>P</i>=0.11).</p><p><strong>Conclusions: </strong>Acupuncture therapy has advantages in clinical efficacy and safety than conventional drugs and other sports rehabilitation therapies in improving post-stroke central facial palsy. However, more high-quality clinical trials are warranted to provide adequate clinical evidence.</p>\",\"PeriodicalId\":34919,\"journal\":{\"name\":\"针刺研究\",\"volume\":\"50 4\",\"pages\":\"467-476\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"针刺研究\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.13702/j.1000-0607.20240426\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"针刺研究","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.13702/j.1000-0607.20240426","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
[Clinical efficacy and safety of acupuncture therapy for central facial palsy after stroke: a systematic review and Meta-analysis].
Objectives: To systematically evaluate the efficacy and safety of acupuncture therapy in the treatment of central facial palsy after stroke.
Methods: A computerized search of articles on acupuncture treatment of central facial palsy was conducted from databases of China National Knowledge Infrastructure(CNKI), Wanfang Data Knowledge Service Platform (Wanfang), VIP Information Chinese Journal Service Platform (VIP) , China Biomedical Literature Database(CBM), Cochrane Library, PubMed, Embase and Web of Science from their inception to September 25th, 2023. The Cochrane risk of bias assessment tool was used to evaluate the risk of bias of all the included literature, and Meta-analysis on the extracted data was conducted using Review Manager 5.4 software.
Results: Eleven studies with a total of 893 patients were finally included, and the bias risks of the included studies were all "some concerns". The results of Meta-analysis suggested that:1) the observation group was superior to the control group in improving the the House-Brackmann facial nerve grading system (H-B) scores (MD=6.41, 95%CI [3.69, 9.14], Z=4.62, P<0.000 01), facial disability index (FDI) scores (somatic function) (MD=2.72, 95%CI [0.31, 5.12], Z=2.21, P=0.03), and clinical effective rate (RR=1.25, 95%CI [1.15, 1.35], Z=5.57, P<0.000 01);2) the observation group was not significantly different from the control group in improving the Toronto facial nerve assessment system (TFGS) scores (MD=3.66, 95%CI [ -2.33, 9.65], Z=1.20, P=0.23), the degrees of facial nerve paralysis (DFNP) scores (MD=4.60, 95%CI [ -1.14, 10.34], Z=1.57, P=0.12), FDI scores (social function) (MD=3.00, 95%CI [ -0.67, 6.66], Z=1.60, P=0.11).
Conclusions: Acupuncture therapy has advantages in clinical efficacy and safety than conventional drugs and other sports rehabilitation therapies in improving post-stroke central facial palsy. However, more high-quality clinical trials are warranted to provide adequate clinical evidence.
期刊介绍：
Acupuncture Research was founded in 1976. It is an acupuncture academic journal supervised by the State Administration of Traditional Chinese Medicine, co-sponsored by the Institute of Acupuncture of the China Academy of Chinese Medical Sciences and the Chinese Acupuncture Association. This journal is characterized by "basic experimental research as the main focus, taking into account clinical research and reporting". It is the only journal in my country that focuses on reporting the mechanism of action of acupuncture.
The journal has been changed to a monthly journal since 2018, published on the 25th of each month, and printed in full color. The manuscript acceptance rate is about 10%, and provincial and above funded projects account for about 80% of the total published papers, reflecting the latest scientific research results in the acupuncture field and has a high academic level. Main columns: mechanism discussion, clinical research, acupuncture anesthesia, meridians and acupoints, theoretical discussion, ideas and methods, literature research, etc.
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