Grant Borne, Mark Knackstedt, Isabella Fabian, Ivan Alvarez, Liam Ordoyne, Rema A Kandula, Ameya Asarkar, Cherie-Ann Nathan, John Pang
{"title":"重大头颈癌手术后肺炎。","authors":"Grant Borne, Mark Knackstedt, Isabella Fabian, Ivan Alvarez, Liam Ordoyne, Rema A Kandula, Ameya Asarkar, Cherie-Ann Nathan, John Pang","doi":"10.1002/hed.28160","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The incidence of postoperative pneumonia (PPNA) in patients undergoing major head and neck cancer surgery has not been well established.</p><p><strong>Methods: </strong>Patients who developed PPNA undergoing major head and neck cancer (HNC) surgery from the Nationwide Inpatient Sample (NIS) from the years 2017 to 2019 (n = 10 037) were analyzed using ICD-10 codes.</p><p><strong>Results: </strong>PPNA developed in 2.8% (n = 285) of patients undergoing major HNC surgery. PPNA patients had longer hospitalizations (15 [10-24] vs. 6 [3-9] days, p < 0.001; median, IQR) and had greater hospital charges (241 308 [166 976-382 982] vs. 104 697 [59 640-181 760], p < 0.001; USD; median, IQR). Regression models revealed that anemia was the greatest predisposing factor for PPNA (OR: 3.3, 95% CI: 2.6-4.2) among other comorbidities such as COPD (OR: 2.0, 95% CI: 1.6-2.7), hypertension (OR: 1.3, 95% CI: 1.0-1.7), and dementia (OR: 1.4, 95% CI: 1.0-1.9).</p><p><strong>Conclusions: </strong>In one of the population's largest data sets, anemia and COPD were the strongest contributing factors to developing PPNA for HNC patients. PPNA was the strongest predictor of increased length of stay and hospital charges in patients undergoing major HNC surgery. Surgical pathways should directly target decreasing PPNA rates to improve outcomes and lower costs.</p>","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Postoperative Pneumonia in Major Head and Neck Cancer Surgery.\",\"authors\":\"Grant Borne, Mark Knackstedt, Isabella Fabian, Ivan Alvarez, Liam Ordoyne, Rema A Kandula, Ameya Asarkar, Cherie-Ann Nathan, John Pang\",\"doi\":\"10.1002/hed.28160\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The incidence of postoperative pneumonia (PPNA) in patients undergoing major head and neck cancer surgery has not been well established.</p><p><strong>Methods: </strong>Patients who developed PPNA undergoing major head and neck cancer (HNC) surgery from the Nationwide Inpatient Sample (NIS) from the years 2017 to 2019 (n = 10 037) were analyzed using ICD-10 codes.</p><p><strong>Results: </strong>PPNA developed in 2.8% (n = 285) of patients undergoing major HNC surgery. PPNA patients had longer hospitalizations (15 [10-24] vs. 6 [3-9] days, p < 0.001; median, IQR) and had greater hospital charges (241 308 [166 976-382 982] vs. 104 697 [59 640-181 760], p < 0.001; USD; median, IQR). Regression models revealed that anemia was the greatest predisposing factor for PPNA (OR: 3.3, 95% CI: 2.6-4.2) among other comorbidities such as COPD (OR: 2.0, 95% CI: 1.6-2.7), hypertension (OR: 1.3, 95% CI: 1.0-1.7), and dementia (OR: 1.4, 95% CI: 1.0-1.9).</p><p><strong>Conclusions: </strong>In one of the population's largest data sets, anemia and COPD were the strongest contributing factors to developing PPNA for HNC patients. PPNA was the strongest predictor of increased length of stay and hospital charges in patients undergoing major HNC surgery. Surgical pathways should directly target decreasing PPNA rates to improve outcomes and lower costs.</p>\",\"PeriodicalId\":55072,\"journal\":{\"name\":\"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-04-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/hed.28160\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OTORHINOLARYNGOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/hed.28160","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
Postoperative Pneumonia in Major Head and Neck Cancer Surgery.
Background: The incidence of postoperative pneumonia (PPNA) in patients undergoing major head and neck cancer surgery has not been well established.
Methods: Patients who developed PPNA undergoing major head and neck cancer (HNC) surgery from the Nationwide Inpatient Sample (NIS) from the years 2017 to 2019 (n = 10 037) were analyzed using ICD-10 codes.
Results: PPNA developed in 2.8% (n = 285) of patients undergoing major HNC surgery. PPNA patients had longer hospitalizations (15 [10-24] vs. 6 [3-9] days, p < 0.001; median, IQR) and had greater hospital charges (241 308 [166 976-382 982] vs. 104 697 [59 640-181 760], p < 0.001; USD; median, IQR). Regression models revealed that anemia was the greatest predisposing factor for PPNA (OR: 3.3, 95% CI: 2.6-4.2) among other comorbidities such as COPD (OR: 2.0, 95% CI: 1.6-2.7), hypertension (OR: 1.3, 95% CI: 1.0-1.7), and dementia (OR: 1.4, 95% CI: 1.0-1.9).
Conclusions: In one of the population's largest data sets, anemia and COPD were the strongest contributing factors to developing PPNA for HNC patients. PPNA was the strongest predictor of increased length of stay and hospital charges in patients undergoing major HNC surgery. Surgical pathways should directly target decreasing PPNA rates to improve outcomes and lower costs.
期刊介绍:
Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.