间歇性θ波爆发刺激对中风后下肢运动恢复的影响:系统回顾和荟萃分析。

IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY
NeuroRehabilitation Pub Date : 2025-03-01 Epub Date: 2025-02-12 DOI:10.1177/10538135241304991
Xinyi Su, Beisi Zheng, Haiping Huang, Shishi Chen, Manting Cao, Jianer Chen
{"title":"间歇性θ波爆发刺激对中风后下肢运动恢复的影响:系统回顾和荟萃分析。","authors":"Xinyi Su, Beisi Zheng, Haiping Huang, Shishi Chen, Manting Cao, Jianer Chen","doi":"10.1177/10538135241304991","DOIUrl":null,"url":null,"abstract":"<p><p>BackgroundIntermittent theta burst stimulation (iTBS) appears to be a potential intervention for enhancing motor recovery in post-stroke. However, the optimal parameters of iTBS protocol for lower limb dysfunction is ambiguous.ObjectiveTo evaluate the efficacy of iTBS in treating lower limb motor impairment after stroke and to explore the optimal stimulation parameters.MethodsRelevant randomized controlled trials (RCTs) were retrieved from seven databases from their inception to May 2024. We defined primary outcomes as Fugl-Meyer Assessment for Lower Extremity (FMA-LE) and Berg Balance Scale (BBS). Subgroup analyses included stroke stage, stimulation sites, dosages and treatment sessions.ResultsThe study results indicated that compared with the sham iTBS group, the iTBS group showed a significant improvement in lower limb motor recovery, balance, gait and activity of daily living (ADL). No significant effect was found in the Motor Evoked Potential amplitude. Subgroup analysis demonstrated that cerebellar iTBS had a therapeutic effect on subacute stroke patients. Furthermore, administrating 1200 pulses per session for a minimum of 15 sessions of iTBS intervention could significantly improve the balance and ADL performance.ConclusioniTBS could enhance lower limb motor function, improving the quality of life in subacute stroke patients with relatively high safety.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":"56 2","pages":"219-233"},"PeriodicalIF":1.8000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Effect of Intermittent Theta Burst Stimulation for Post-Stroke Lower Limb Motor Recovery: A Systematic Review and Meta-Analysis.\",\"authors\":\"Xinyi Su, Beisi Zheng, Haiping Huang, Shishi Chen, Manting Cao, Jianer Chen\",\"doi\":\"10.1177/10538135241304991\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>BackgroundIntermittent theta burst stimulation (iTBS) appears to be a potential intervention for enhancing motor recovery in post-stroke. However, the optimal parameters of iTBS protocol for lower limb dysfunction is ambiguous.ObjectiveTo evaluate the efficacy of iTBS in treating lower limb motor impairment after stroke and to explore the optimal stimulation parameters.MethodsRelevant randomized controlled trials (RCTs) were retrieved from seven databases from their inception to May 2024. We defined primary outcomes as Fugl-Meyer Assessment for Lower Extremity (FMA-LE) and Berg Balance Scale (BBS). Subgroup analyses included stroke stage, stimulation sites, dosages and treatment sessions.ResultsThe study results indicated that compared with the sham iTBS group, the iTBS group showed a significant improvement in lower limb motor recovery, balance, gait and activity of daily living (ADL). No significant effect was found in the Motor Evoked Potential amplitude. Subgroup analysis demonstrated that cerebellar iTBS had a therapeutic effect on subacute stroke patients. Furthermore, administrating 1200 pulses per session for a minimum of 15 sessions of iTBS intervention could significantly improve the balance and ADL performance.ConclusioniTBS could enhance lower limb motor function, improving the quality of life in subacute stroke patients with relatively high safety.</p>\",\"PeriodicalId\":19717,\"journal\":{\"name\":\"NeuroRehabilitation\",\"volume\":\"56 2\",\"pages\":\"219-233\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"NeuroRehabilitation\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/10538135241304991\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/2/12 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"NeuroRehabilitation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/10538135241304991","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/12 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0

摘要

背景:间歇性θ波爆发刺激(iTBS)似乎是一种潜在的干预措施,可以增强脑卒中后的运动恢复。然而,iTBS方案治疗下肢功能障碍的最佳参数尚不明确。目的评价iTBS治疗脑卒中后下肢运动障碍的疗效,探讨最佳刺激参数。方法从7个数据库中检索自建立至2024年5月的相关随机对照试验(rct)。我们将主要结局定义为Fugl-Meyer下肢评估(FMA-LE)和Berg平衡量表(BBS)。亚组分析包括脑卒中分期、刺激部位、剂量和治疗时间。结果研究结果显示,与假iTBS组相比,iTBS组在下肢运动恢复、平衡、步态和日常生活活动(ADL)方面均有显著改善。运动诱发电位振幅未见明显变化。亚组分析表明,小脑iTBS对亚急性脑卒中患者有治疗作用。此外,在至少15次的iTBS干预中,每次1200次脉冲可以显著改善平衡和ADL性能。结论itbs可增强亚急性脑卒中患者下肢运动功能,改善患者生活质量,安全性较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Effect of Intermittent Theta Burst Stimulation for Post-Stroke Lower Limb Motor Recovery: A Systematic Review and Meta-Analysis.

BackgroundIntermittent theta burst stimulation (iTBS) appears to be a potential intervention for enhancing motor recovery in post-stroke. However, the optimal parameters of iTBS protocol for lower limb dysfunction is ambiguous.ObjectiveTo evaluate the efficacy of iTBS in treating lower limb motor impairment after stroke and to explore the optimal stimulation parameters.MethodsRelevant randomized controlled trials (RCTs) were retrieved from seven databases from their inception to May 2024. We defined primary outcomes as Fugl-Meyer Assessment for Lower Extremity (FMA-LE) and Berg Balance Scale (BBS). Subgroup analyses included stroke stage, stimulation sites, dosages and treatment sessions.ResultsThe study results indicated that compared with the sham iTBS group, the iTBS group showed a significant improvement in lower limb motor recovery, balance, gait and activity of daily living (ADL). No significant effect was found in the Motor Evoked Potential amplitude. Subgroup analysis demonstrated that cerebellar iTBS had a therapeutic effect on subacute stroke patients. Furthermore, administrating 1200 pulses per session for a minimum of 15 sessions of iTBS intervention could significantly improve the balance and ADL performance.ConclusioniTBS could enhance lower limb motor function, improving the quality of life in subacute stroke patients with relatively high safety.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
NeuroRehabilitation
NeuroRehabilitation CLINICAL NEUROLOGY-REHABILITATION
CiteScore
3.20
自引率
0.00%
发文量
178
审稿时长
6-12 weeks
期刊介绍: NeuroRehabilitation, an international, interdisciplinary, peer-reviewed journal, publishes manuscripts focused on scientifically based, practical information relevant to all aspects of neurologic rehabilitation. We publish unsolicited papers detailing original work/research that covers the full life span and range of neurological disabilities including stroke, spinal cord injury, traumatic brain injury, neuromuscular disease and other neurological disorders. We also publish thematically organized issues that focus on specific clinical disorders, types of therapy and age groups. Proposals for thematic issues and suggestions for issue editors are welcomed.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信