血压升高和抗高血压药物处方趋势。

IF 6.9 1区 医学 Q1 PERIPHERAL VASCULAR DISEASE
Hypertension Pub Date : 2025-06-01 Epub Date: 2025-04-22 DOI:10.1161/HYPERTENSIONAHA.124.24316
Ashutosh Kumar, Nicole L Therrien, John I Ogwuegbu, Jun Soo Lee, Hilary K Wall, John M Flack, Sandra L Jackson
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引用次数: 0

摘要

背景:许多药物具有升高血压的作用,这可能对高血压患者的血压控制产生负面影响。本研究考察了在美国个体中单独和同时使用的血压升高和抗高血压药物的处方填充趋势。方法:使用IQVIA患者总追踪数据库中的全国样本报告同时和单独填充血压升高和降压药的季度趋势,覆盖美国所有零售处方填充的94%。我们确定了1387种产品含有升高血压的药物,240种产品含有抗高血压药物。使用2017年第一季度的百分比变化和连接点回归的平均季度百分比变化来呈现总体趋势,并按性别和年龄组(0-17岁、18-44岁、45-64岁、65-74岁和≥75岁)划分。结果:从2017年到2023年,单独使用血压升高药物的充血量保持稳定,单独使用抗高血压药物的充血量增加(增加9.5%;10.1% - 11.0%;结论:这些结果首次提供了全国范围内同时使用血压升高和抗高血压药物的趋势,表明这种趋势正在增加。我们的研究结果可能为临床医生对高血压患者的药物选择提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Blood Pressure-Elevating and Antihypertensive Medication Prescription Trends.

Background: Many medications can have blood pressure (BP)-elevating effects, which might negatively impact BP control among people with hypertension. This study examines trends in prescription fills for BP-elevating and antihypertensive medications, individually and concurrently, among US individuals.

Methods: Quarterly trends of individual and concurrent fills for BP-elevating and antihypertensive medications were reported using the nationwide sample from IQVIA's Total Patient Tracker database, covering 94% of all retail prescription fills in the United States. We identified 1387 products containing BP-elevating medications and 240 products containing antihypertensive medications. Percentage change from Q1/2017 and average quarterly percent change from the joinpoint regression were used to present trends overall and by sex and age group (0-17, 18-44, 45-64, 65-74, and ≥75 years).

Results: From 2017 to 2023, fills remained stable for BP-elevating medications alone and increased for antihypertensive medications alone (9.5% increase; from 10.1% to 11.0%; P<0.001). Concurrent fills for antihypertensive and BP-elevating medications increased by 15.9% (from 5.4% to 6.2%; P<0.001). Fills for BP-elevating medications were higher among adult women compared with men; among women aged 18 to 44 years, this was primarily due to the use of combined oral contraceptives. In Q4/2023, fills for BP-elevating medications were most common among those aged 65 to 74 years (women=30.7%; men=20.4%).

Conclusions: These results provide the first nationwide trends in concurrent prescription fills for BP-elevating and antihypertensive medications, indicating an increasing trend. Our findings might inform clinician decision-making regarding medication selection for patients with hypertension.

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来源期刊
Hypertension
Hypertension 医学-外周血管病
CiteScore
15.90
自引率
4.80%
发文量
1006
审稿时长
1 months
期刊介绍: Hypertension presents top-tier articles on high blood pressure in each monthly release. These articles delve into basic science, clinical treatment, and prevention of hypertension and associated cardiovascular, metabolic, and renal conditions. Renowned for their lasting significance, these papers contribute to advancing our understanding and management of hypertension-related issues.
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