Giacomo Dal Fabbro, Giovanni Balboni, Stefano Di Paolo, Giorgio Varchetta, Alberto Grassi, Giulio Maria Marcheggiani Muccioli, Stefano Zaffagnini
{"title":"外侧闭合楔形胫骨高位截骨术治疗膝关节内侧骨关节炎:平均11年随访分析。","authors":"Giacomo Dal Fabbro, Giovanni Balboni, Stefano Di Paolo, Giorgio Varchetta, Alberto Grassi, Giulio Maria Marcheggiani Muccioli, Stefano Zaffagnini","doi":"10.1007/s00264-025-06525-0","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To assess long term survivorship, patient reported (PROMs) and radiological outcomes, and rate of adverse events and hardware removal after lateral closing wedge high tibial osteotomy (CWHTO) for the treatment of medial knee osteoarthritis (OA) and varus malalignment.</p><p><strong>Methods: </strong>Retrospective analysis of patients who underwent isolated CWHTO for medial OA in varus knee between 2009 and 2019 at the same institution was performed. Surgical failure was defined as conversion to total knee arthroplasty (TKA) or need for osteotomy revision procedure for varus recurrence, while clinical failure was defined by a Lysholm score under 65 points. Lysholm score, Visual Analogue Scale for pain (VAS), and patients' satisfaction with the treatment were evaluated. Radiographic parameters assessed included OA degree with the Kellgren Lawrence scale (KL), hip-knee-ankle angle (HKA), medial proximal tibial angle (MPTA), lateral distal femoral angle (LDFA), joint line convergence angle (JLCA), and posterior tibial slope (PTS). Adverse events and rate of hardware removal procedures were recorded through follow up visits and clinical records. Survival analysis was conducted through Kaplan-Meier method with surgical and clinical failure as endpoints.</p><p><strong>Results: </strong>70 knees (mean age at surgery 43.3 years) were included in the survivorship analysis at a mean follow up of 11.6 ± 3.4 years. A failure rate of 12.85% (9/70) was recorded during the follow up period, with a survivorship of 92% and 75% at ten and 15 years of follow up, respectively. Mean Lysholm score and VAS at follow up were above the PASS threshold reported in literature. The 75.7% of patients were satisfied with the treatment. Radiological follow up indicated a residual mechanical varus of 2.1°, a decrease of 0.7° of intra articular deformity (JLCA), no change in PTS nor in KL index. The adverse events rate recorded was 5.7% (4/70). In nine knees (14.7%) among the patients survived from surgical failure a subsequent hardware removal procedure was performed.</p><p><strong>Conclusion: </strong>CWHTO represents a safe procedure, which resulted in high survivorship (92% and 75% at ten and 15 years follow up, respectively), with satisfactory PROMs and radiological outcomes at long term follow up in patients affected by medial OA and varus malalignment.</p><p><strong>Level of evidence: </strong>5, Case Series.</p>","PeriodicalId":14450,"journal":{"name":"International Orthopaedics","volume":" ","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Lateral closing wedge high tibial osteotomy procedure for the treatment of medial knee osteoarthritis: eleven years mean follow up analysis.\",\"authors\":\"Giacomo Dal Fabbro, Giovanni Balboni, Stefano Di Paolo, Giorgio Varchetta, Alberto Grassi, Giulio Maria Marcheggiani Muccioli, Stefano Zaffagnini\",\"doi\":\"10.1007/s00264-025-06525-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To assess long term survivorship, patient reported (PROMs) and radiological outcomes, and rate of adverse events and hardware removal after lateral closing wedge high tibial osteotomy (CWHTO) for the treatment of medial knee osteoarthritis (OA) and varus malalignment.</p><p><strong>Methods: </strong>Retrospective analysis of patients who underwent isolated CWHTO for medial OA in varus knee between 2009 and 2019 at the same institution was performed. Surgical failure was defined as conversion to total knee arthroplasty (TKA) or need for osteotomy revision procedure for varus recurrence, while clinical failure was defined by a Lysholm score under 65 points. Lysholm score, Visual Analogue Scale for pain (VAS), and patients' satisfaction with the treatment were evaluated. Radiographic parameters assessed included OA degree with the Kellgren Lawrence scale (KL), hip-knee-ankle angle (HKA), medial proximal tibial angle (MPTA), lateral distal femoral angle (LDFA), joint line convergence angle (JLCA), and posterior tibial slope (PTS). Adverse events and rate of hardware removal procedures were recorded through follow up visits and clinical records. Survival analysis was conducted through Kaplan-Meier method with surgical and clinical failure as endpoints.</p><p><strong>Results: </strong>70 knees (mean age at surgery 43.3 years) were included in the survivorship analysis at a mean follow up of 11.6 ± 3.4 years. A failure rate of 12.85% (9/70) was recorded during the follow up period, with a survivorship of 92% and 75% at ten and 15 years of follow up, respectively. Mean Lysholm score and VAS at follow up were above the PASS threshold reported in literature. The 75.7% of patients were satisfied with the treatment. Radiological follow up indicated a residual mechanical varus of 2.1°, a decrease of 0.7° of intra articular deformity (JLCA), no change in PTS nor in KL index. The adverse events rate recorded was 5.7% (4/70). 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引用次数: 0
摘要
目的:评估外侧闭合楔形高位胫骨截骨术(CWHTO)治疗内侧膝骨关节炎(OA)和内翻错位后的长期生存率、患者报告(PROMs)和放射学结果、不良事件发生率和硬体移除率。方法:回顾性分析2009年至2019年同一医院因膝内翻内侧骨关节炎接受孤立性CWHTO治疗的患者。手术失败被定义为转换为全膝关节置换术(TKA)或因内翻复发需要截骨翻修手术,而临床失败被定义为Lysholm评分低于65分。评定Lysholm评分、疼痛视觉模拟评分(VAS)及患者对治疗的满意度。影像学参数评估包括骨性关节炎程度(Kellgren Lawrence scale, KL)、髋关节-膝关节-踝关节角(HKA)、胫骨内侧近端角(MPTA)、股骨外侧远端角(LDFA)、关节线收敛角(JLCA)和胫骨后斜度(PTS)。通过随访和临床记录记录不良事件和硬体取出手术率。通过Kaplan-Meier法进行生存分析,以手术和临床失败为终点。结果:70例膝关节(平均手术年龄43.3岁)纳入生存分析,平均随访11.6±3.4年。随访期间的失败率为12.85%(9/70),随访10年和15年的生存率分别为92%和75%。随访时平均Lysholm评分和VAS均高于文献报道的PASS阈值。75.7%的患者对治疗满意。放射学随访显示残余机械内翻2.1°,关节内畸形(JLCA)减少0.7°,PTS和KL指数无变化。不良事件发生率为5.7%(4/70)。在手术失败的患者中,有9例(14.7%)膝关节存活,随后进行了硬体取出手术。结论:CWHTO是一种安全的手术,其生存率高(随访10年和15年分别为92%和75%),对内侧OA和内翻错位患者的长期随访具有令人满意的PROMs和放射学结果。证据等级:5,案例系列。
Lateral closing wedge high tibial osteotomy procedure for the treatment of medial knee osteoarthritis: eleven years mean follow up analysis.
Purpose: To assess long term survivorship, patient reported (PROMs) and radiological outcomes, and rate of adverse events and hardware removal after lateral closing wedge high tibial osteotomy (CWHTO) for the treatment of medial knee osteoarthritis (OA) and varus malalignment.
Methods: Retrospective analysis of patients who underwent isolated CWHTO for medial OA in varus knee between 2009 and 2019 at the same institution was performed. Surgical failure was defined as conversion to total knee arthroplasty (TKA) or need for osteotomy revision procedure for varus recurrence, while clinical failure was defined by a Lysholm score under 65 points. Lysholm score, Visual Analogue Scale for pain (VAS), and patients' satisfaction with the treatment were evaluated. Radiographic parameters assessed included OA degree with the Kellgren Lawrence scale (KL), hip-knee-ankle angle (HKA), medial proximal tibial angle (MPTA), lateral distal femoral angle (LDFA), joint line convergence angle (JLCA), and posterior tibial slope (PTS). Adverse events and rate of hardware removal procedures were recorded through follow up visits and clinical records. Survival analysis was conducted through Kaplan-Meier method with surgical and clinical failure as endpoints.
Results: 70 knees (mean age at surgery 43.3 years) were included in the survivorship analysis at a mean follow up of 11.6 ± 3.4 years. A failure rate of 12.85% (9/70) was recorded during the follow up period, with a survivorship of 92% and 75% at ten and 15 years of follow up, respectively. Mean Lysholm score and VAS at follow up were above the PASS threshold reported in literature. The 75.7% of patients were satisfied with the treatment. Radiological follow up indicated a residual mechanical varus of 2.1°, a decrease of 0.7° of intra articular deformity (JLCA), no change in PTS nor in KL index. The adverse events rate recorded was 5.7% (4/70). In nine knees (14.7%) among the patients survived from surgical failure a subsequent hardware removal procedure was performed.
Conclusion: CWHTO represents a safe procedure, which resulted in high survivorship (92% and 75% at ten and 15 years follow up, respectively), with satisfactory PROMs and radiological outcomes at long term follow up in patients affected by medial OA and varus malalignment.
期刊介绍:
International Orthopaedics, the Official Journal of the Société Internationale de Chirurgie Orthopédique et de Traumatologie (SICOT) , publishes original papers from all over the world. The articles deal with clinical orthopaedic surgery or basic research directly connected with orthopaedic surgery. International Orthopaedics will also link all the members of SICOT by means of an insert that will be concerned with SICOT matters.
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