Xiao-Xue Li, Han Yu, Shang-Hong Song, Xiao-Hua Liu, Yu-Ning Zheng, Zhao-Hui Li, Jia-Mei Chen, Chun-Xin Xing, Xiao-Feng He, Guang-Hua Lu
{"title":"黄花萱草茎叶中4个新的酚类化合物。","authors":"Xiao-Xue Li, Han Yu, Shang-Hong Song, Xiao-Hua Liu, Yu-Ning Zheng, Zhao-Hui Li, Jia-Mei Chen, Chun-Xin Xing, Xiao-Feng He, Guang-Hua Lu","doi":"10.1080/10286020.2025.2483806","DOIUrl":null,"url":null,"abstract":"<p><p>Four new phenolic compounds, hemerodiphenylethanes A-D (<b>1-4</b>), along with eight known compounds methyl 2,4-dihydroxy-6-[2-(4-hydroxyphenyl) ethyl] benzoate (<b>5</b>), methyl 2,4-dihydroxy-6-(4-hydroxyphenethyl)-3-methylbenzoate (<b>6</b>), neochlorogenic acid (<b>7</b>), isoquercetin (<b>8</b>), isorhamnetin-3-O-β-D-galactoside (<b>9</b>), velutin (<b>10</b>), rutin (<b>11</b>), and (+)-syringaresinol (<b>12</b>), were isolated from the stems and leaves of <i>Hemerocallis citrina</i> Baroni (Daylily). Their structures were elucidated based on HR-ESI-MS, 1D- and 2D-NMR spectra, and ECD calculations. Among them, both compounds <b>10</b> and <b>12</b> were isolated from the genus <i>Hemerocallis</i>, and compounds <b>5</b> and <b>6</b> were isolated from this plant species for the first time. These compounds showed antioxidant activity as determined by IC<sub>50</sub> values of DPPH and ABTS<sup>+</sup> in a radical scavenging experiment.</p>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":" ","pages":"1-11"},"PeriodicalIF":1.3000,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Four new phenolic compounds from stems and leaves of <i>Hemerocallis citrina</i> (Daylily).\",\"authors\":\"Xiao-Xue Li, Han Yu, Shang-Hong Song, Xiao-Hua Liu, Yu-Ning Zheng, Zhao-Hui Li, Jia-Mei Chen, Chun-Xin Xing, Xiao-Feng He, Guang-Hua Lu\",\"doi\":\"10.1080/10286020.2025.2483806\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Four new phenolic compounds, hemerodiphenylethanes A-D (<b>1-4</b>), along with eight known compounds methyl 2,4-dihydroxy-6-[2-(4-hydroxyphenyl) ethyl] benzoate (<b>5</b>), methyl 2,4-dihydroxy-6-(4-hydroxyphenethyl)-3-methylbenzoate (<b>6</b>), neochlorogenic acid (<b>7</b>), isoquercetin (<b>8</b>), isorhamnetin-3-O-β-D-galactoside (<b>9</b>), velutin (<b>10</b>), rutin (<b>11</b>), and (+)-syringaresinol (<b>12</b>), were isolated from the stems and leaves of <i>Hemerocallis citrina</i> Baroni (Daylily). Their structures were elucidated based on HR-ESI-MS, 1D- and 2D-NMR spectra, and ECD calculations. Among them, both compounds <b>10</b> and <b>12</b> were isolated from the genus <i>Hemerocallis</i>, and compounds <b>5</b> and <b>6</b> were isolated from this plant species for the first time. These compounds showed antioxidant activity as determined by IC<sub>50</sub> values of DPPH and ABTS<sup>+</sup> in a radical scavenging experiment.</p>\",\"PeriodicalId\":15180,\"journal\":{\"name\":\"Journal of Asian Natural Products Research\",\"volume\":\" \",\"pages\":\"1-11\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-04-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Asian Natural Products Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/10286020.2025.2483806\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Asian Natural Products Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/10286020.2025.2483806","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
摘要
从萱草（萱草）的茎叶中分离得到4个新的酚类化合物：六苯基二苯乙烷A-D(1-4)，以及8个已知化合物2,4-二羟基-6-[2-（4-羟基苯基）乙基]苯甲酸甲酯(5)、2,4-二羟基-6-（4-羟基苯基）-3-甲基苯甲酸甲酯(6)、新绿原酸(7)、异槲皮素(8)、异鼠李苷-3- o -β- d -半乳苷(9)、芦丁（10）、芦丁（11）和(+)-丁香醇（12）。基于HR-ESI-MS、1D和2D-NMR谱以及ECD计算对其结构进行了鉴定。其中，化合物10和12均为从萱草属植物中分离得到，化合物5和6为首次从该植物中分离得到。通过DPPH和ABTS+在自由基清除实验中的IC50值测定，这些化合物具有抗氧化活性。
Four new phenolic compounds from stems and leaves of Hemerocallis citrina (Daylily).
Four new phenolic compounds, hemerodiphenylethanes A-D (1-4), along with eight known compounds methyl 2,4-dihydroxy-6-[2-(4-hydroxyphenyl) ethyl] benzoate (5), methyl 2,4-dihydroxy-6-(4-hydroxyphenethyl)-3-methylbenzoate (6), neochlorogenic acid (7), isoquercetin (8), isorhamnetin-3-O-β-D-galactoside (9), velutin (10), rutin (11), and (+)-syringaresinol (12), were isolated from the stems and leaves of Hemerocallis citrina Baroni (Daylily). Their structures were elucidated based on HR-ESI-MS, 1D- and 2D-NMR spectra, and ECD calculations. Among them, both compounds 10 and 12 were isolated from the genus Hemerocallis, and compounds 5 and 6 were isolated from this plant species for the first time. These compounds showed antioxidant activity as determined by IC50 values of DPPH and ABTS+ in a radical scavenging experiment.
期刊介绍：
The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures.
All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
